CMPD_CHEMBLID CANONICAL_SMILES PCHEMBL_VALUE ASSAY_CHEMBLID CHEMBL101311 CN(C)CC(O)COc1ccc(Nc2nccc(Nc3cc(Cl)ccc3Cl)n2)cc1 6.7 CHEMBL1963785 CHEMBL1081312 Nc1ncnc2c1c(nn2C3CCCC3)c4cnc5[nH]ccc5c4 7.8 CHEMBL1963785 CHEMBL1164180 CN1CCN(CC1)c2ccc(cn2)c3cnc4NCCN(Cc5cc(Cl)ccc5C(F)(F)F)c4c3 6.1 CHEMBL1963785 CHEMBL1164265 CN1CCN(CC1)c2ccc(cn2)c3cnc4NCCN(Cc5c(F)ccc(F)c5Cl)c4c3 7 CHEMBL1963785 CHEMBL1165511 Fc1ccc(cc1)C(Cl)Cn2ncc3c(Nc4cccc(F)c4)ncnc23 5.52 CHEMBL1166971 CHEMBL1221411 CN1C(=O)C(=Cc2cnc(Nc3cccc(NC(=O)CN)c3)nc12)c4c(Cl)cccc4Cl 10.7 CHEMBL1227835 CHEMBL1223343 CN1C(=O)C(=Cc2cnc(NCc3cccc(N)c3)nc12)c4c(Cl)cccc4Cl 8.1 CHEMBL1227835 CHEMBL1223344 CN1C(=O)C(=Cc2cnc(NCc3cccc(N)c3)nc12)c4ccccc4Cl 7.22 CHEMBL1227835 CHEMBL1223410 CN1C(=O)C(=Cc2cnc(NCc3cccc(N)c3)nc12)c4ccccc4 5.7 CHEMBL1227835 CHEMBL1223411 CN1C(=O)C(=Cc2cnc(NCc3cccc(N)c3)nc12)c4c(F)cccc4F 7.4 CHEMBL1227835 CHEMBL1223412 CN1C(=O)C(=Cc2cnc(NCc3cccc(N)c3)nc12)c4ccccc4Br 7.4 CHEMBL1227835 CHEMBL1223413 CSc1cccc(CNc2ncc3C=C(C(=O)N(C)c3n2)c4c(Cl)cccc4Cl)c1 7.16 CHEMBL1227835 CHEMBL1223481 CCCCCCNc1cccc(CNc2ncc3C=C(C(=O)N(C)c3n2)c4c(Cl)cccc4Cl)c1 6.05 CHEMBL1227835 CHEMBL1223482 CN1C(=O)C(=Cc2cnc(NCc3cccc(NC(=O)CN)c3)nc12)c4c(Cl)cccc4Cl 7.7 CHEMBL1227835 CHEMBL1223483 CN1C(=O)C(=Cc2cnc(NCc3cccc(c3)C(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nc12)c6c(Cl)cccc6Cl 7.7 CHEMBL1227835 CHEMBL1241473 COc1cc(Nc2ncc(c(Nc3ccccc3C(=O)N)n2)[N+](=O)[O-])cc(OC)c1OC 6.9 CHEMBL1963785 CHEMBL1241489 CC(C)n1nc(c2ccc3ccccc3c2)c4c(N)ncnc14 7.16 CHEMBL2033711 CHEMBL1242754 CC(C)n1nc(c2cnc3ccccc3c2)c4c(N)ncnc14 5.8 CHEMBL2033711 CHEMBL1336 CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 6.8 CHEMBL1963785 CHEMBL1629808 CSc1nc(NCc2cccc(Br)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 7.19 CHEMBL1837743 CHEMBL1773092 Fc1ccc(cc1)C(Cl)Cn2ncc3c(NCc4ccccn4)ncnc23 5.68 CHEMBL1776290 CHEMBL1775035 ClC(Cn1ncc2c(Nc3ccccc3)nc(SCCN4CCOCC4)nc12)c5ccccc5 6.82 CHEMBL1776290 CHEMBL1775036 ClC(Cn1ncc2c(Nc3cccc(Cl)c3)nc(SCCN4CCOCC4)nc12)c5ccccc5 6.75 CHEMBL3395760 CHEMBL1775037 ClC(Cn1ncc2c(NCCc3ccccc3)nc(SCCN4CCOCC4)nc12)c5ccccc5 6.57 CHEMBL1776290 CHEMBL1775038 Fc1ccc(CNc2nc(SCCN3CCOCC3)nc4c2cnn4CC(Cl)c5ccccc5)cc1 6.24 CHEMBL1776290 CHEMBL1775039 ClC(Cn1ncc2c(NCc3ccccc3)nc(SCCN4CCOCC4)nc12)c5ccccc5 7.05 CHEMBL1776290 CHEMBL1775040 CCCNc1nc(SCCN2CCOCC2)nc3c1cnn3CC(Cl)c4ccccc4 6.47 CHEMBL1776290 CHEMBL1775041 ClC(Cn1ncc2c(Nc3cccc(Cl)c3)nc(nc12)N4CCOCC4)c5ccccc5 6.41 CHEMBL1776290 CHEMBL1775042 OCCNc1nc(NCCc2ccccc2)c3cnn(\C=C/c4ccccc4)c3n1 6.66 CHEMBL1776290 CHEMBL1775043 CS(=O)(=O)c1nc(NCc2ccccc2)c3cnn(CC(Cl)c4ccccc4)c3n1 5.7 CHEMBL1776290 CHEMBL1775044 CCCNc1nc(nc2c1cnn2\C=C/c3ccccc3)S(=O)(=O)C 6.14 CHEMBL1776290 CHEMBL1775045 ClC(Cn1ncc2c(NCc3ccccn3)ncnc12)c4ccc(Cl)cc4 5.92 CHEMBL1776290 CHEMBL1775046 ClC(Cn1ncc2c(NCc3ccncc3)ncnc12)c4ccc(Cl)cc4 6.18 CHEMBL1776290 CHEMBL1775047 Fc1ccc(cc1)C(Cl)Cn2ncc3c(NCc4ccncc4)ncnc23 5.8 CHEMBL1776290 CHEMBL1785020 COc1ccc2cc(ccc2c1)c3nn(C(C)C)c4ncnc(N)c34 6.13 CHEMBL2033711 CHEMBL1785021 CCOc1ccc2cc(ccc2c1)c3nn(C(C)C)c4ncnc(N)c34 5.8 CHEMBL2033711 CHEMBL1825138 CC(Oc1cc(cnc1N)c2cnn(c2)C3CCNCC3)c4c(Cl)ccc(F)c4Cl 5.8 CHEMBL1963785 CHEMBL1835870 Nc1nc(Nc2ccc(cc2)[C@@H]3CC[C@H](CC3)N4CCOCC4)nn1c5ccccn5 6.4 CHEMBL1958992 CHEMBL1836675 CSc1nc(NCc2ccccc2F)c3cnn(CC(C)c4ccccc4)c3n1 6 CHEMBL1837743 CHEMBL1836676 CSc1nc(NCc2ccc(F)cc2)c3cnn(CC(C)c4ccccc4)c3n1 5.73 CHEMBL1837743 CHEMBL1836677 CSc1nc(NCc2ccccc2Cl)c3cnn(CC(C)c4ccccc4)c3n1 6.11 CHEMBL1837743 CHEMBL1836680 CSc1nc(Nc2cccc(Br)c2)c3cnn(CC(C)c4ccccc4)c3n1 5.97 CHEMBL1837743 CHEMBL1836681 Fc1cccc(CNc2ncnc3c2cnn3CCc4ccccc4)c1 5.31 CHEMBL1837743 CHEMBL191003 Nc1nc(Nc2ccc(cc2)S(=O)(=O)N)nn1C(=O)c3c(F)cccc3F 6.4 CHEMBL1963785 CHEMBL1949855 Clc1cccc2C(=O)NC=Nc12 4.4 CHEMBL1963785 CHEMBL196363 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4ncnc(N)c34)c1 6.8 CHEMBL1963785 CHEMBL1964441 CNCC#Cc1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cccc(C)c4)cc3 6.8 CHEMBL1963785 CHEMBL1964718 CC1=CN2CC(=O)NN=C2C=C1 4 CHEMBL1963785 CHEMBL1965169 Cc1ccc(cc1)c2cc3nc(Br)cnc3[nH]2 6.1 CHEMBL1963785 CHEMBL1965170 COc1ccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)c5cnn(CC(O)CO)c5)cc1 8.7 CHEMBL1963785 CHEMBL1965570 Nc1ncc(c2cocc2)c3scc(c4ccc(NC(=O)Nc5ccccc5F)cc4)c13 7 CHEMBL1963785 CHEMBL1965988 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)C#CCN)c1 6.6 CHEMBL1963785 CHEMBL1966514 Nc1ncc(c2cocc2)c3scc(c4ccc(NC(=O)Nc5cccc(F)c5)cc4)c13 7.5 CHEMBL1963785 CHEMBL1966836 Cn1nc(N)c2c(ccnc12)c3ccc(NC(=O)Nc4ccc(F)c(c4)C(F)(F)F)cc3 6.7 CHEMBL1963785 CHEMBL1966842 COc1ccc(CN(C)C)cc1Nc2nccc(n2)c3c(nc4sccn34)c5cccc(NC(=O)Cc6ccccc6)c5 5.7 CHEMBL1963785 CHEMBL1967116 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)c5cnn(C)c5)c1 8.8 CHEMBL1963785 CHEMBL1967252 Cc1n[nH]c2ccc(cc12)c3cccnc3 4.6 CHEMBL1963785 CHEMBL1967513 FC(F)(F)c1cccc(NC(=O)Nc2ccnc3ccc(Cl)cc23)n1 5.7 CHEMBL1963785 CHEMBL1967531 Nc1ncnc2scc(c3ccc(NC(=O)Nc4ccccc4)cc3)c12 6.6 CHEMBL1963785 CHEMBL1967878 CN1CCN(CC1)c2ccc(Nc3ncc(F)c(NC4C5CC(C=C5)C4C(=O)N)n3)cc2C 7.4 CHEMBL1963785 CHEMBL1968130 Nc1nnc2cncc(Cl)n12 4.6 CHEMBL1963785 CHEMBL1968590 CNC(=O)C=Cc1cnc(N)c2c(csc12)c3ccc4sc(C)nc4c3 7.3 CHEMBL1963785 CHEMBL1968868 FC(F)(F)c1ccc2c(NC(=O)Nc3cccc(n3)C#N)ccnc2c1 5.6 CHEMBL1963785 CHEMBL1969102 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)c5cn[nH]c5)c1 8.8 CHEMBL1963785 CHEMBL1969156 Nc1nccc2cnc(c3ccccc3)n12 4.6 CHEMBL1963785 CHEMBL1969190 COc1ccc(c2ccc(NC(=O)Nc3cc(F)cc(F)c3)cc2)c4c(N)noc14 6.3 CHEMBL1963785 CHEMBL1969502 O=C(Nc1cc2C(=O)NN=Cc3c[nH]c(c1)c23)C4CC4c5ccccc5 7 CHEMBL1963785 CHEMBL1969537 S=C1NN=C2N1C3=NNC(=S)N3c4sc5CCCc5c24 7.1 CHEMBL1963785 CHEMBL1969588 Clc1cc(cc(NCc2ccccc2)n1)c3c[nH]c4ncccc34 6.3 CHEMBL1963785 CHEMBL1970083 Nc1ncc(c2ccncc2)c3scc(c4ccc(NC(=O)Nc5cc(ccc5F)C(F)(F)F)cc4)c13 8 CHEMBL1963785 CHEMBL1970104 CC(C)(C)c1ccc2nc([nH]c2c1)c3n[nH]c4ccccc34 6.8 CHEMBL1963785 CHEMBL1970142 CNC(=O)C(C)n1cc(cn1)c2cnc(N)c3c(csc23)c4ccc(NC(=O)Nc5ccc(C)cc5)cc4 8.4 CHEMBL1963785 CHEMBL1970290 CCN(CC)CCNC(=O)c1cccc(c1)n2nc(cc2NC(=O)Nc3cccc4ccccc34)C(C)(C)C 5.8 CHEMBL1963785 CHEMBL1970317 Cn1cc(cn1)c2cnc(N)c3c(csc23)c4ccc(NC(=O)Nc5cccc(F)c5)cc4 8.7 CHEMBL1963785 CHEMBL1970879 COc1cc(ccc1NC(=O)c2cc3ccccc3n2C)c4nn(C5CCC(CC5)N6CCN(CC6)C(=O)C)c7ncnc(N)c47 6.8 CHEMBL1963785 CHEMBL1971519 Nc1n[nH]c2cccc(c3ccc(F)cc3)c12 4.8 CHEMBL1963785 CHEMBL1971534 NC(=O)c1cc2ccncc2s1 4.1 CHEMBL1963785 CHEMBL1971947 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)C#Cc5cccnc5)c1 7.2 CHEMBL1963785 CHEMBL1972220 Nc1ncc(c2cnn(CCO)c2)c3scc(c4ccc(NC(=O)Nc5ccc(OC(F)F)cc5)cc4)c13 8.8 CHEMBL1963785 CHEMBL1972355 COc1c2C(=O)C=C(C)Oc2cc(O)c1c3nc4ccccc4[nH]3 6.1 CHEMBL1963785 CHEMBL1972934 Nc1ncnc2sccc12 4.7 CHEMBL1963785 CHEMBL1973178 COc1ccc(c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)c4c(N)noc14 6.7 CHEMBL1963785 CHEMBL1973211 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)C#CCN5CCCC5)c1 6.6 CHEMBL1963785 CHEMBL1973359 NC(=O)c1ccc2nc(cn2c1)c3oc(cc3)[N+](=O)[O-] 6.4 CHEMBL1963785 CHEMBL1973720 NC1CCC(CC1)Nc2nc(Cl)cc(n2)c3c[nH]c4ncccc34 5.8 CHEMBL1963785 CHEMBL1974254 CCOc1ccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)c5cnn(C)c5)cc1 9.2 CHEMBL1963785 CHEMBL1974328 Cc1cccc(Nc2nc(NC3CCCCC3N)cnc2C(=O)N)c1 6.6 CHEMBL1963785 CHEMBL1974416 Fc1cccc(C(=O)Nc2cnc3[nH]cc(c4ccccc4)c3c2)c1F 6.6 CHEMBL1963785 CHEMBL1974664 COc1ccc(C=NNc2ncnc3c4ccccc4[nH]c23)cc1OC 7.2 CHEMBL1963785 CHEMBL1974875 OC(=O)c1csc2C(=O)NCCNc12 4.2 CHEMBL1963785 CHEMBL1975212 Nc1ncnc2scc(c3ccccc3)c12 5.6 CHEMBL1963785 CHEMBL1975503 Nc1ccc(cc1)C2=CC=CN3C(=O)NN=C23 4.3 CHEMBL1963785 CHEMBL1975903 COc1ccccc1c2ccnc(Nc3cccc(c3)S(=O)(=O)C)n2 6.3 CHEMBL1963785 CHEMBL1975921 Brc1cnc2NC(=O)Nc2c1 4.8 CHEMBL1963785 CHEMBL1975927 COc1ccc(cc1)n2ccc3cnc(Nc4cc(OC)c(OC)c(OC)c4)nc23 6.3 CHEMBL1963785 CHEMBL1976040 CN1CCN(CC1)c2ccc(Nc3ncc4C(=O)N(CC=C)N(c5cccc(n5)C(C)(C)O)c4n3)cc2 6.5 CHEMBL1963785 CHEMBL1976134 c1cc2cc(cnc2[nH]1)c3ccc4cn[nH]c4c3 7.3 CHEMBL1963785 CHEMBL1976196 [O-][N+](=O)c1ccc(NC(=O)N2CCc3[nH]c4c(Cl)cc(Cl)cc4c3C2)cc1 5.6 CHEMBL1963785 CHEMBL1976420 CCc1c([nH]c2nccnc12)c3ccc(cc3)C(C)(C)O 5.9 CHEMBL1963785 CHEMBL1976872 CC(=O)Nc1cc2ccccn2n1 4.2 CHEMBL1963785 CHEMBL1977041 COC(=O)c1c(C)n2ncnc(N)c2c1c3ccc(NC(=O)Nc4ccccc4)cc3 6.9 CHEMBL1963785 CHEMBL1977134 Nc1c(cnc2c(cnn12)c3ccc4OCOc4c3)c5ccc(NC(=O)Nc6cccc(c6)C(F)(F)F)cc5 6.7 CHEMBL1963785 CHEMBL1977138 CC(Nc1cncc(n1)n2cnc3ccc(cc23)C#N)c4ccccc4F 6.2 CHEMBL1963785 CHEMBL1977148 COc1ccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)c5cnn(CCO)c5)cc1 9.6 CHEMBL1963785 CHEMBL1977931 CC(=O)c1ccccc1c2ncnc3[nH]ccc23 4.1 CHEMBL1963785 CHEMBL1978166 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)C#CCCCCCCCCN)c1 6.9 CHEMBL1963785 CHEMBL1978167 Cn1cc(c2cc3nc(Br)cnc3[nH]2)c4ccccc14 5.9 CHEMBL1963785 CHEMBL1978371 Clc1ccc(cc1)C2CC(=C(C#N)C(=O)C2C(=O)c3ccccc3)c4ccccc4 5.9 CHEMBL1963785 CHEMBL1978562 Cn1cc(c2cc3nc(Br)cnc3[nH]2)c4cc(ccc14)C#N 6.1 CHEMBL1963785 CHEMBL1979252 FC(F)(F)c1cccc(CNC2=C(Nc3ccncc3)C(=O)C2=O)c1 6.4 CHEMBL1963785 CHEMBL1979577 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)C#CC(C)(C)N)c1 6.5 CHEMBL1963785 CHEMBL1979690 CN1CCN(CC1)c2ccc(Nc3ncc(Cl)c(Nc4ccc5[nH]ncc5c4)n3)cc2 7 CHEMBL1963785 CHEMBL1979883 CN(C)CC#Cc1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cccc(C)c4)cc3 6.8 CHEMBL1963785 CHEMBL1980167 CN(C)c1ccc(cc1)c2cc(nc(NS(=O)(=O)c3ccc(N)cc3)n2)c4ccc(cc4)[N+](=O)[O-] 5.9 CHEMBL1963785 CHEMBL1980297 Nc1ncc(c2cnn(CCO)c2)c3scc(c4ccc(NC(=O)Nc5cccc(F)c5)cc4)c13 8.5 CHEMBL1963785 CHEMBL1980329 Oc1ccc(cc1)c2ccc3C(=Cc4ccc[nH]4)C(=O)Nc3c2 7.3 CHEMBL1963785 CHEMBL1980376 Cc1cccc(c1)c2cccc3onc(N)c23 4.6 CHEMBL1963785 CHEMBL1980407 NC(COc1cncc(c1)c2ccc3NC(=O)C(=Cc4ccc[nH]4)c3c2)Cc5ccccc5 7.2 CHEMBL1963785 CHEMBL1980671 Nc1ncnc2Nc3ccccc3NC(=O)c12 5.7 CHEMBL1963785 CHEMBL1980763 CC(C)Cc1nc(Nc2ccc(N3CCOCC3)c(Cl)c2)nc4[nH]ccc14 5.6 CHEMBL1963785 CHEMBL1980904 Nc1n[nH]c2cccc(c3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)c(F)c3)c12 6.5 CHEMBL1963785 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 7 CHEMBL1963785 CHEMBL1981047 COC(C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N4CCN(C)CC4)c2C1)c5ccccc5 8.6 CHEMBL1963785 CHEMBL1981492 COC(=O)c1c(N)nc2ccccn12 4 CHEMBL1963785 CHEMBL1981744 FC(F)(F)c1cccc(NC(=O)Nc2ccnc3cc(Cl)ccc23)n1 5.4 CHEMBL1963785 CHEMBL1982465 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)C#CCN5CCOCC5)c1 7.4 CHEMBL1963785 CHEMBL1982466 Cc1ccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)c5cnn(C)c5)cc1 8.6 CHEMBL1963785 CHEMBL1982476 CNC(=O)c1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3 9.3 CHEMBL1963785 CHEMBL1982711 NC(=O)c1ccc(cc1)c2c[nH]c3nccc(Cl)c23 6 CHEMBL1963785 CHEMBL1982957 NC(=O)c1cccc(c1)c2cnc3[nH]cc(c4ccccc4)c3c2 7.3 CHEMBL1963785 CHEMBL1983025 CCC(N)(CC)C#Cc1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cccc(C)c4)cc3 6.3 CHEMBL1963785 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c3cc(Nc4ncc(c(NC5CCC5)n4)C(F)(F)F)ccc23 6.6 CHEMBL1963785 CHEMBL1983268 CN1CCN(CC1)c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cc(F)cc(F)c5)cc34)c(NC6CCOCC6)c2 6.5 CHEMBL1963785 CHEMBL1983348 CCCCN(CCC#N)C(=O)c1ccc2nc([nH]c2c1)c3n[nH]c4ccccc34 5.7 CHEMBL1963785 CHEMBL1983573 Nc1nnc2cccc(c3ccc(C=C)cc3)n12 4.4 CHEMBL1963785 CHEMBL1983575 Oc1c(Br)cc(C=NNC(=O)Nc2ccccc2)cc1Br 6.2 CHEMBL1963785 CHEMBL1983630 O=C1Cc2cc(cnc2N1)c3ccccc3 4.1 CHEMBL1963785 CHEMBL1983640 Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)c3coc4c(cnc(N)c34)C#CCN5CCOCC5)c1 6.4 CHEMBL1963785 CHEMBL1983715 CCNc1nc(C)c(s1)c2ccnc(Nc3ccc(cc3)N4CCN(CC4)C(=O)C)n2 6.6 CHEMBL1963785 CHEMBL1983923 CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(C=Cc4ccccc4)n2 6.7 CHEMBL1963785 CHEMBL1983963 Cc1cccc(NC(=O)Nc2ccc(cc2)c3coc4ncnc(N)c34)c1 6.7 CHEMBL1963785 CHEMBL1983980 OCc1ccc(cc1)c2sc(nc2C(=O)O)N3CCc4cccc(C(=O)Nc5nc6ccccc6s5)c4C3 5.8 CHEMBL1963785 CHEMBL1984162 COCCOC1CCC(CC1)n2nc(c3ccc(Nc4oc5c(C)cc(C)cc5n4)cc3)c6c(N)ncnc26 6.4 CHEMBL1963785 CHEMBL1985367 Cc1ccnc(Nc2cc(C)nc(n2)c3ccccc3)c1 6 CHEMBL1963785 CHEMBL1985888 Cn1nc(N)c2c(ccnc12)c3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)cc3 6.7 CHEMBL1963785 CHEMBL1986590 O=C1Nc2ccccc2C1=Cc3c[nH]c4ccccc34 5.9 CHEMBL1963785 CHEMBL1986899 Cc1ccc(NCc2ccc(nc2)c3ccc(F)cc3)cc1 5.7 CHEMBL1963785 CHEMBL1986943 OC1CCC(CC1)Nc2nc(Cl)cc(n2)c3c[nH]c4ncccc34 6.2 CHEMBL1963785 CHEMBL1987034 NS(=O)(=O)c1cccc(Nc2ncc(Br)c(Nc3ccc(OCC#N)cc3)n2)c1 7 CHEMBL1963785 CHEMBL1987054 COCCOC1CCC(CC1)n2nc(c3ccc(Nc4oc5c(Cl)cc(C)cc5n4)cc3)c6c(N)ncnc26 6.3 CHEMBL1963785 CHEMBL1988075 Cc1ccc(cn1)c2cnc(N)c3c(csc23)c4ccc(NC(=O)Nc5cccc(F)c5)cc4 7.4 CHEMBL1963785 CHEMBL1988141 CCC(=O)Nc1ccc(C(=O)N2CCNCC2)c(O)c1 6 CHEMBL1963785 CHEMBL1988300 Nc1ccc(cc1)c2csc3c(C=Cc4nc5ccccc5[nH]4)cnc(N)c23 7.3 CHEMBL1963785 CHEMBL1988387 Cn1cc(cn1)c2cnc(N)c3c(csc23)c4ccc(NC(=O)Nc5ccc(OC(F)F)cc5)cc4 8.6 CHEMBL1963785 CHEMBL1988437 CNC(=O)c1ccccc1Sc2ccc3c(C=Cc4ccccn4)n[nH]c3c2 8.5 CHEMBL1963785 CHEMBL1988581 CN(C)CC1=C(O)C2=NC(=CC(=O)N2C=C1)C 7.1 CHEMBL1963785 CHEMBL1988692 CC(C)NC1=NNC(=O)C1=Cc2cc3ccccc3[nH]2 6.6 CHEMBL1963785 CHEMBL1988717 Cn1cc(cn1)c2cnn3c(N)c(cnc23)c4ccc(NC(=O)Nc5cccc(c5)C(F)(F)F)cc4 7.8 CHEMBL1963785 CHEMBL1988838 Cc1cnc(Nc2cccc(c2)S(=O)(=O)N)nc1Nc3ccc(OCC(=O)N)cc3 6.7 CHEMBL1963785 CHEMBL1989267 COc1cc(ccc1NC(=O)c2cc3ccccc3n2C)c4csc5c(C=CC(=O)NCCN(C)C)cnc(N)c45 7.9 CHEMBL1963785 CHEMBL1989471 CC(C)c1ccc2C(=O)c3c(C)ccnc3Nc2c1 6.6 CHEMBL1963785 CHEMBL1990884 Cc1cc(C)c2oc(Nc3ccc(cc3F)c4cccc(C(=O)N)c4N)nc2c1 7 CHEMBL1963785 CHEMBL1991095 Nc1c(cnc2c(Br)cnn12)C#N 4.1 CHEMBL1963785 CHEMBL1991734 CN1c2ccc(N)cc2C(c3ccccc3)c4cc(N)ccc14 6.2 CHEMBL1963785 CHEMBL1992042 Fc1ccc(cc1)C(=O)Nc2cccc(c2)C3Nc4ccc5ccccc5c4C6C=CCC36 5.9 CHEMBL1963785 CHEMBL1992125 COc1cc(Nc2ncnc(n2)N3CCCc4cc(C)ccc34)cc(OC)c1OC 5.7 CHEMBL1963785 CHEMBL1992306 CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cccc(c3)C(F)(F)F)cc2)ccn1 6.2 CHEMBL1963785 CHEMBL1992473 CN(C)c1c(NC(=O)c2c(F)cccc2F)cccc1c3nc4sccn4c3c5ccnc(Nc6cccc(c6)N7CCOCC7)n5 6.3 CHEMBL1963785 CHEMBL1992581 FC(F)Sc1ccc(NC(=O)Cc2ccc(cc2)c3cccnc3)cc1 6.7 CHEMBL1963785 CHEMBL1992673 Clc1ccc2NC(=O)n3ncnc3c2c1 4.4 CHEMBL1963785 CHEMBL1992937 Cc1ccc(Nc2nc3ccc(cc3[nH]2)[N+](=O)[O-])nc1 6.1 CHEMBL1963785 CHEMBL1993335 Cn1cc(c2cc3nc(Br)cnc3[nH]2)c4cc(F)ccc14 6.8 CHEMBL1963785 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc2nc(Nc3cc(OC)c(OC)c(OC)c3)ncc2Cl 8.1 CHEMBL1963785 CHEMBL1993877 Nc1ncnc2c1c(cn2C3CCCC3)C#C 6 CHEMBL1963785 CHEMBL1993904 NC(=O)c1cc2c(cnc(N)c2s1)c3ccc(Nc4oc5ccccc5n4)cc3 5.8 CHEMBL1963785 CHEMBL1993941 CCCn1cc(cn1)c2cnc(N)c3c(csc23)c4ccc(NC(=O)Nc5cccc(F)c5)cc4 8.9 CHEMBL1963785 CHEMBL1994159 CC(=O)c1cccc(c1)c2ccc3nccn3n2 4.3 CHEMBL1963785 CHEMBL1994321 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)C#CCNS(=O)(=O)C)c1 7.1 CHEMBL1963785 CHEMBL1994555 CCc1c([nH]c2nccnc12)c3ccc(cc3)C(=O)C 5.7 CHEMBL1963785 CHEMBL1994808 Cc1nnc(c2ccccc2)c(n1)C#N 4 CHEMBL1963785 CHEMBL1995765 NC1=CC(=O)NN1c2ccccn2 4.9 CHEMBL1963785 CHEMBL1996048 Cc1ccc(cc1)c2cc3c(NCCN)ccc(C(=O)N)c3[nH]2 5.7 CHEMBL1963785 CHEMBL1996066 Nc1nc2ccc(cc2n1c3nc(cs3)c4ccccc4)C#N 8 CHEMBL1963785 CHEMBL1996255 Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)c3c(F)ccc4[nH]nc(N)c34)c1 6.3 CHEMBL1963785 CHEMBL1996646 COc1cccc(OC)c1CNc2nc(NC3CCCCC3)nc4ccc(Cl)cc24 6.4 CHEMBL1963785 CHEMBL1996649 CCN(CC)CCCNC(=O)c1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cccc(F)c4)cc3 8.1 CHEMBL1963785 CHEMBL1996702 COc1cc(ccc1O)c2ccc3C(=O)Nc4cc(ccc4Nc3c2)C(=O)NCCCN(C)C 6.6 CHEMBL1963785 CHEMBL1996979 Fc1cccc(F)c1C(=O)Nc2cnc3[nH]cc(c4ccccc4)c3c2 8 CHEMBL1963785 CHEMBL1997119 Nc1ncc2cccc(c3ccccc3)n12 4.6 CHEMBL1963785 CHEMBL1997129 O=C1NCCc2[nH]c(cc12)c3ccnc(C=Cc4ccccc4)c3 6.3 CHEMBL1963785 CHEMBL1997275 COc1ccc2[nH]cc(C=C3C(=O)Nc4ccccc34)c2c1 5.9 CHEMBL1963785 CHEMBL1997617 CN1CCN(CC1)C2CCC(CC2)n3cc(c4ccc(Oc5ccccc5)cc4)c6c(N)ncnc36 8.4 CHEMBL1963785 CHEMBL1997822 Cc1cc2cc(ccc2[nH]1)c3csc4c(cnc(N)c34)c5cccc(c5)S(=O)(=O)C 8.4 CHEMBL1963785 CHEMBL1997924 C(Nc1nc(Nc2cc([nH]n2)C3CC3)c4sccc4n1)c5ccccc5 8 CHEMBL1963785 CHEMBL1998228 Clc1cc2nnc(c3ccccc3)n2cn1 4.2 CHEMBL1963785 CHEMBL1998585 Nc1ncnc2scc(c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12 7.5 CHEMBL1963785 CHEMBL1999112 CCOC(=O)C1=C2SC(=Cc3occc3)C(=O)N2C(=C(C#N)C1c4occc4)N 7.1 CHEMBL1963785 CHEMBL1999120 CC(C)C1=CC(=O)NC2=C1C(=O)NN2 4.2 CHEMBL1963785 CHEMBL1999414 CCN(CC)CCCNC(=O)c1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cccc(C)c4)cc3 8.1 CHEMBL1963785 CHEMBL1999484 CNc1nc(C)c(s1)c2ccnc(Nc3ccc(cc3)N4CCNCC4)n2 7.1 CHEMBL1963785 CHEMBL1999590 Cc1cc(c2ccccc2)n(n1)c3cc(NN=Cc4occc4)ncn3 6.3 CHEMBL1963785 CHEMBL1999811 Oc1ccc(C=NNC(=O)Nc2cccc3nsnc23)c(O)c1 6.4 CHEMBL1963785 CHEMBL2000335 Cc1ccc(NC(=O)Nc2ccc(cc2)c3csc4ncnc(N)c34)cc1C 6.5 CHEMBL1963785 CHEMBL2000652 Nc1n[nH]c2cccc(c3ccc(NC(=O)Nc4cccc(Cl)c4)c(F)c3)c12 6.3 CHEMBL1963785 CHEMBL2001228 Fc1ccccc1C(=O)Nc2cccc(c2Cl)c3nc4sccn4c3c5ccnc(Nc6cccc(c6)N7CCOCC7)n5 5.9 CHEMBL1963785 CHEMBL2001257 CCN(CC)CC#Cc1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cccc(C)c4)cc3 6.3 CHEMBL1963785 CHEMBL2001485 CC(C(=O)N(C)C)n1cc(cn1)c2cnc(N)c3c(csc23)c4ccc(NC(=O)Nc5ccc(C)cc5)cc4 7.6 CHEMBL1963785 CHEMBL2001613 Brc1ccc2NNC(=O)c2c1 4.4 CHEMBL1963785 CHEMBL2002099 N#CCC(C1CCCC1)n2cc(cn2)c3ncnc4[nH]ccc34 5.5 CHEMBL1963785 CHEMBL2002105 Nc1n[nH]c2ncc(Br)cc12 4.1 CHEMBL1963785 CHEMBL2002165 CC(O)Cn1cc(cn1)c2cnc(N)c3c(csc23)c4ccc(NC(=O)Nc5cccc(F)c5)cc4 9.1 CHEMBL1963785 CHEMBL2002432 CC(C)Nc1nccc(Nc2ncc(s2)c3ccccc3)n1 7.1 CHEMBL1963785 CHEMBL2002450 COc1ccc(c2ccc(N)cc2)c3cnoc13 4.2 CHEMBL1963785 CHEMBL2002586 Clc1cc(Nc2nc(NC3CC3)c4sccc4n2)ccc1N5CCOCC5 5.9 CHEMBL1963785 CHEMBL2003657 CC(C)S(=O)(=O)n1c(N)nc2ccc(cc12)c3c(nc4sccn34)c5ccc(F)cc5 6.3 CHEMBL1963785 CHEMBL2003785 Fc1cccc(CNc2ncnc3[nH]cnc23)c1 4.3 CHEMBL1963785 CHEMBL2004025 COCOc1cccc(OCOC)c1c2ccc(NS(=O)(=O)C)cc2C(=O)OC 5.7 CHEMBL1963785 CHEMBL2004118 CCc1nc(Nc2ccc(N3CCOCC3)c(Cl)c2)nc4[nH]ccc14 5.8 CHEMBL1963785 CHEMBL2004290 COc1ccc(NC(=O)Nc2ccc(cc2)c3csc4c(cnc(N)c34)c5cnn(CC(C)(C)O)c5)cc1 8.5 CHEMBL1963785 CHEMBL2004311 Cc1cc(C)cc(NC(=O)Nc2ccc(c(C)c2)c3cccc4C(=O)NCc34)c1 6.2 CHEMBL1963785 CHEMBL2004515 C1Oc2ccc(cc2O1)c3ncnc4[nH]ccc34 5.1 CHEMBL1963785 CHEMBL2004637 CCN(CCN)C(=O)c1cccc(c1)n2nc(cc2NC(=O)Nc3cccc4ccccc34)C(C)(C)C 5.8 CHEMBL1963785 CHEMBL2004716 CCN(CC)CCNC(=O)C=Cc1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cccc(C)c4)cc3 8.6 CHEMBL1963785 CHEMBL2005449 Cc1cc(Nc2nc(Cl)cc(NCc3ccccc3)n2)n[nH]1 6.1 CHEMBL1963785 CHEMBL2005478 COc1ccc2c(c1)c(cn2C)c3cc4nc(Br)cnc4[nH]3 6.7 CHEMBL1963785 CHEMBL2005631 CNC(=O)c1cnc(N)c2c(csc12)c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3 8.7 CHEMBL1963785 CHEMBL2005886 Cc1cc(cc2[nH]c(nc12)C3=C(NCC(O)c4cccc(Cl)c4)C=CNC3=O)N5CCOCC5 6.6 CHEMBL1963785 CHEMBL2006564 CCN(C(=O)C)c1ccc(Nc2nc(NC3CC3)c4nc[nH]c4n2)cc1 7 CHEMBL1963785 CHEMBL2006765 CCCNC(=O)c1ccc(Nc2nc(NCC(F)(F)F)c3cc[nH]c3n2)cc1 6.3 CHEMBL1963785 CHEMBL2006778 CNC(=O)C=Cc1cnc(N)c2c(csc12)c3cc(F)c4[nH]c(C)cc4c3 8.7 CHEMBL1963785 CHEMBL2007097 NC1=NC(=O)Nc2sccc12 4.2 CHEMBL1963785 CHEMBL2022856 C[C@@H](O)Cn1cc(cn1)c2cnc(N)c3c(csc23)c4ccc(NC(=O)Nc5cccc(F)c5)cc4 9.1 CHEMBL2065344 CHEMBL2030556 CC(C)n1nc(c2cc3c(Cl)cccc3[nH]2)c4c(N)ncnc14 6.55 CHEMBL2033711 CHEMBL2030558 COc1ccc(cc1C)c2nn(CC3CCNCC3)c4ncnc(N)c24 5.26 CHEMBL2033711 CHEMBL2030560 Nc1nc2ccc(cc2[nH]1)C(=O)c3ccccc3 5 CHEMBL2033711 CHEMBL203493 C(Cc1ccccc1)Nc2ncnc3c2cnn3\C=C/c4ccccc4 5.01 CHEMBL2073050 CHEMBL206046 Ic1ccc(cc1)C(=O)Nc2nnc(CCc3ccccc3)s2 6.4 CHEMBL859157 CHEMBL206575 Cc1ccc(cc1C)N2NC(=O)\C(=C\c3oc(cc3)c4ccc(C)c(Cl)c4)\C2=O 5.3 CHEMBL859157 CHEMBL207360 Clc1ccc(cc1Cl)N2NC(=O)\C(=C\c3cccc(OCc4ccccc4)c3)\C2=O 6 CHEMBL859157 CHEMBL207471 Nc1[nH]cnc2nnc(c3ccc(Cl)cc3)c12 6.3 CHEMBL859157 CHEMBL207986 Ic1ccccc1C(=O)Nc2nnc(CCc3ccccc3)s2 5.89 CHEMBL859157 CHEMBL209617 Ic1ccc(cc1)N2NC(=O)\C(=C\c3ccccc3)\C2=O 6.22 CHEMBL859157 CHEMBL210766 Ic1ccc(\C=C/2\C(=O)NN(C2=O)c3ccc(I)cc3)cc1 6.1 CHEMBL859157 CHEMBL230686 Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)c5c(Cl)cccc5Cl 7.7 CHEMBL923928 CHEMBL231220 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN4CCCC4)nc12)c5c(O)cccc5Cl 8.3 CHEMBL923928 CHEMBL231524 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN4CCCC4)nc12)c5cc(N)ccc5Cl 7.8 CHEMBL923928 CHEMBL235756 CSc1nc(NCCc2cccc(F)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.64 CHEMBL1056610 CHEMBL235757 CSc1nc(NCCc2ccccc2Cl)c3cnn(CC(Cl)c4ccccc4)c3n1 6.5 CHEMBL1056610 CHEMBL235758 CSc1nc(NCCc2cccc(Cl)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.7 CHEMBL1056610 CHEMBL236375 CSc1nc(NCc2ccccc2Cl)c3cnn(CC(Cl)c4ccccc4)c3n1 7.05 CHEMBL1837743 CHEMBL238304 CSc1nc(NCCc2ccccc2)c3cnn(CC(Cl)c4ccc(Cl)cc4)c3n1 6.96 CHEMBL1056610 CHEMBL238559 CSc1nc(Nc2cccc(F)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.4 CHEMBL962773 CHEMBL238561 CSc1nc(Nc2cccc(Br)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 7.22 CHEMBL1056610 CHEMBL238774 ClC(Cn1ncc2c(Nc3cccc(Cl)c3)ncnc12)c4ccccc4 6.62 CHEMBL1837743 CHEMBL2397796 Fc1cccc(CNc2ncnc3c2cnn3CC(Cl)c4ccc(Br)cc4)c1 7.26 CHEMBL2399913 CHEMBL2397797 Fc1ccc(cc1)C(Cl)Cn2ncc3c(Nc4cccc(Cl)c4)ncnc23 6.75 CHEMBL2399913 CHEMBL2397798 Fc1ccc(cc1)C(Cl)Cn2ncc3c(Nc4cccc(Br)c4)ncnc23 6.18 CHEMBL2399913 CHEMBL2397799 ClC(Cn1ncc2c(Nc3cccc(Br)c3)ncnc12)c4ccccc4 6.59 CHEMBL2399913 CHEMBL2397800 Fc1cccc(Nc2ncnc3c2cnn3CC(Cl)c4ccccc4)c1 5.84 CHEMBL2399913 CHEMBL2397801 ClC(Cn1ncc2c(Nc3ccccc3)ncnc12)c4ccccc4 6.05 CHEMBL2399913 CHEMBL2397802 ClC(Cn1ncc2c(Nc3ccccc3)ncnc12)c4ccc(Br)cc4 6.22 CHEMBL2399913 CHEMBL2397803 ClC(Cn1ncc2c(NCc3ccccc3)ncnc12)c4ccc(Br)cc4 5.88 CHEMBL2399913 CHEMBL2397804 ClC(Cn1ncc2c(NCc3cccc(Cl)c3)ncnc12)c4ccc(Br)cc4 7.68 CHEMBL2399913 CHEMBL2397805 ClC(Cn1ncc2c(NCc3ccccc3Cl)ncnc12)c4ccc(Br)cc4 8.3 CHEMBL2399913 CHEMBL2397806 ClC(Cn1ncc2c(NCc3ccc(Cl)cc3)ncnc12)c4ccc(Br)cc4 6.85 CHEMBL2399913 CHEMBL2397807 ClC(Cn1ncc2c(NCc3cc(Cl)ccc3Cl)ncnc12)c4ccc(Br)cc4 5.48 CHEMBL2399913 CHEMBL2397808 ClC(Cn1ncc2c(NCc3ccc(Cl)c(Cl)c3)ncnc12)c4ccc(Br)cc4 5.96 CHEMBL2399913 CHEMBL2397809 Fc1ccc(CNc2ncnc3c2cnn3CC(Cl)c4ccc(Br)cc4)cc1 5.6 CHEMBL2399913 CHEMBL2397810 Fc1ccc(F)c(CNc2ncnc3c2cnn3CC(Cl)c4ccc(Br)cc4)c1 5.57 CHEMBL2399913 CHEMBL2397812 ClC(Cn1ncc2c(NCc3ccc(Br)cc3)ncnc12)c4ccc(Br)cc4 5.52 CHEMBL2399913 CHEMBL2397814 ClC(Cn1ncc2c(NCc3cccc(Br)c3)ncnc12)c4ccc(Br)cc4 5.9 CHEMBL2399913 CHEMBL2397815 COc1cccc(CNc2ncnc3c2cnn3CC(Cl)c4ccc(Br)cc4)c1 5.32 CHEMBL2399913 CHEMBL2397816 FC(F)(F)c1cc(CNc2ncnc3c2cnn3CC(Cl)c4ccc(Br)cc4)cc(c1)C(F)(F)F 5.74 CHEMBL2399913 CHEMBL2397817 Cc1ccc(cc1)C(Cl)Cn2ncc3c(Nc4ccccc4)ncnc23 7.22 CHEMBL2399913 CHEMBL2397818 ClC(Cn1ncc2c(Nc3ccccc3)ncnc12)c4ccc(I)cc4 7.3 CHEMBL2399913 CHEMBL2408778 Nc1ncnc2c1c(nn2c3cccc(c3)c4cnnn4CCCCCC(=O)NO)c5ccc(Cl)cc5 5.63 CHEMBL2410768 CHEMBL241539 CSc1nc(NCc2cccc(F)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.5 CHEMBL1056610 CHEMBL241540 CSc1nc(NCc2ccc(F)cc2)c3cnn(CC(Cl)c4ccccc4)c3n1 7 CHEMBL1056610 CHEMBL241749 CSc1nc(NCc2ccccc2)c3cnn(CC(Cl)c4ccc(Cl)cc4)c3n1 6.96 CHEMBL1056610 CHEMBL241750 CSc1nc(NCc2ccccc2)c3cnn(CC(Cl)c4ccc(F)cc4)c3n1 6.6 CHEMBL1056610 CHEMBL242865 OC(=O)c1ccccc1Nc2ccnc(Nc3ccc(cc3)[N+](=O)[O-])n2 6.1 CHEMBL1963785 CHEMBL243088 OC(=O)c1ccccc1Nc2ccnc(Nc3cccc(O)c3)n2 6.5 CHEMBL1963785 CHEMBL245800 NCc1ccc(cc1)c2ccc3ncc(C#N)c(N[C@@H]4C[C@H]4c5ccccc5)c3c2 6.11 CHEMBL923923 CHEMBL248044 COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c4ccccc4)c2cc1OC 6.02 CHEMBL923923 CHEMBL248221 COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c4ccccc4)c2cc1OCCCN5CCOCC5 5.75 CHEMBL923923 CHEMBL248222 COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c4ccccc4)c2cc1OCCCc5cccnc5 5.75 CHEMBL923923 CHEMBL24828 COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC4CCN(C)CC4 7.5 CHEMBL1963785 CHEMBL248391 COc1cc2c(N[C@@H]3C[C@H]3c4ccccc4)c(cnc2cc1OCCCc5cccnc5)C#N 6.52 CHEMBL923923 CHEMBL248392 COc1cc2c(N[C@@H]3C[C@H]3c4ccccc4)c(cnc2cc1OCCCN5CCOCC5)C#N 6.7 CHEMBL923923 CHEMBL248393 COc1cc2c(N[C@@H]3C[C@H]3c4ccccc4)c(cnc2cc1OCCCN5CCN(C)CC5)C#N 7.36 CHEMBL923923 CHEMBL249819 Cc1cc(cc2nnc(Nc3ccc(cc3)C(=O)N4CCS(=O)(=O)CC4)nc12)c5cc(O)ccc5Cl 8.38 CHEMBL923928 CHEMBL249820 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)N)nc12)c4cc(O)ccc4Cl 8.11 CHEMBL923928 CHEMBL249821 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN4CCCC4)nc12)c5cc(O)ccc5Cl 8.52 CHEMBL923928 CHEMBL250019 CN(CCN1CCCC1)S(=O)(=O)c2ccc(Nc3nnc4cc(cc(C)c4n3)c5cc(O)ccc5Cl)cc2 9.52 CHEMBL923928 CHEMBL250021 CCN(CCN1CCCC1)S(=O)(=O)c2ccc(Nc3nnc4cc(cc(C)c4n3)c5cc(O)ccc5Cl)cc2 9.4 CHEMBL923928 CHEMBL250213 Cc1cc(cc2nnc(Nc3ccc(CCCN4CCCC4)cc3)nc12)c5cc(O)ccc5Cl 10.21 CHEMBL923928 CHEMBL250214 Cc1cc(cc2nnc(Nc3ccc(cc3)C(=O)N4CCNCC4)nc12)c5cc(O)ccc5Cl 8.77 CHEMBL923928 CHEMBL250218 CC(C)N(CCN1CCCC1)S(=O)(=O)c2ccc(Nc3nnc4cc(cc(C)c4n3)c5cc(O)ccc5Cl)cc2 8.54 CHEMBL923928 CHEMBL250423 CN(CCN1CCOCC1)S(=O)(=O)c2ccc(Nc3nnc4cc(cc(C)c4n3)c5cc(O)ccc5Cl)cc2 8.29 CHEMBL923928 CHEMBL250623 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)N4CCNCC4)nc12)c5cc(O)ccc5Cl 8.36 CHEMBL923928 CHEMBL250625 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)C4CCNCC4)nc12)c5cc(O)ccc5Cl 8.46 CHEMBL923928 CHEMBL250821 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN4CCCC4)nc12)c5c(Cl)ccc(O)c5F 8.89 CHEMBL923928 CHEMBL251015 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN4CCCC4)nc12)c5cccc6[nH]ccc56 7.62 CHEMBL923928 CHEMBL253969 NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc3c(F)cc(Br)cc3F 7.1 CHEMBL1963785 CHEMBL255164 Clc1ccccc1C(=O)Nc2nnc(SCc3ccc(Br)cc3)s2 6.65 CHEMBL932076 CHEMBL255165 [O-][N+](=O)c1ccc(CSc2nnc(NC(=O)c3ccc(F)cc3)s2)cc1 6.68 CHEMBL932076 CHEMBL255225 Fc1ccc(CSc2nnc(NC(=O)c3ccc(Cl)cc3)s2)cc1 6.98 CHEMBL932076 CHEMBL255324 Fc1ccc(cc1)C(=O)Nc2nnc(SCc3ccc(Br)cc3)s2 7.05 CHEMBL932076 CHEMBL255368 Fc1cccc(CSc2nnc(NC(=O)c3ccc(Cl)cc3)s2)c1 6.66 CHEMBL932076 CHEMBL255522 [O-][N+](=O)c1ccc(CSc2nnc(NC(=O)c3ccccc3Cl)s2)cc1 7.08 CHEMBL932076 CHEMBL255738 Fc1ccc(CSc2nnc(NC(=O)c3ccc(F)cc3)s2)cc1 7.36 CHEMBL932076 CHEMBL256101 Cc1cc(cc2nnc(Nc3ccc(OCC[N+]4([O-])CCCC4)cc3)nc12)c5c(Cl)cccc5Cl 8.69 CHEMBL934545 CHEMBL259084 OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4c3n2)c5c(F)cccc5F)cc1 6.8 CHEMBL1963785 CHEMBL260092 Nc1ncnc2NCCC(=Nc12)c3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)cc3 7.1 CHEMBL1963785 CHEMBL261827 Fc1ccc(cc1)C(Cl)Cn2ncc3c(NCc4cccc(F)c4)ncnc23 7 CHEMBL948149 CHEMBL262623 Nc1ncnc2NCCC(=Nc12)c3ccccc3 5.4 CHEMBL1963785 CHEMBL268825 Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)c5ccccc5Cl 7.38 CHEMBL923928 CHEMBL270286 Fc1ccc(CNc2ncnc3c2cnn3CC(Cl)c4ccc(F)cc4)cc1 6.7 CHEMBL948149 CHEMBL270452 COc1ccc(CSc2nnc(NC(=O)c3ccccc3Cl)s2)cc1 5.9 CHEMBL932076 CHEMBL270454 Clc1ccccc1C(=O)Nc2nnc(SCc3ccccc3)s2 6.04 CHEMBL932076 CHEMBL270492 Fc1ccc(cc1)C(Cl)Cn2ncc3c(NCc4ccccc4F)ncnc23 7.7 CHEMBL948149 CHEMBL270958 Fc1ccccc1CNc2ncnc3c2cnn3CC(Cl)c4ccccc4 6.14 CHEMBL948149 CHEMBL271008 Fc1ccc(cc1)C(=O)Nc2nnc(SCc3cccc(Cl)c3)s2 6.43 CHEMBL932076 CHEMBL271009 Clc1ccc(cc1)C(=O)Nc2nnc(SCc3ccccc3)s2 6.4 CHEMBL932076 CHEMBL271010 Fc1ccc(CSc2nnc(NC(=O)c3ccccc3Cl)s2)cc1 6.39 CHEMBL932076 CHEMBL272169 Fc1ccc(CNc2ncnc3c2cnn3CC(Cl)c4ccccc4)cc1 5.7 CHEMBL948149 CHEMBL272288 Fc1ccc(cc1)C(=O)Nc2nnc(SCc3cccc(F)c3)s2 6.78 CHEMBL932076 CHEMBL272938 Cc1cccc(NC(=O)Nc2ccc(cc2)c3cncc4[nH]nc(N)c34)c1 6.2 CHEMBL1963785 CHEMBL272947 COc1ccc(CSc2nnc(NC(=O)c3ccc(Cl)cc3)s2)cc1 6.72 CHEMBL932076 CHEMBL272999 Clc1ccc(cc1)C(=O)Nc2nnc(SCc3cccc(Cl)c3)s2 7.14 CHEMBL932076 CHEMBL273090 Fc1ccc(cc1)C(Cl)Cn2ncc3c(NCc4ccccc4Cl)ncnc23 6.7 CHEMBL948149 CHEMBL288280 CSc1nc(NCc2ccccc2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.59 CHEMBL1056610 CHEMBL289125 CSc1nc(NCCc2ccccc2)c3cnn(CC(Cl)c4ccccc4)c3n1 5.14 CHEMBL962773 CHEMBL289959 N(c1ccccc1)c2ncnc3ccccc23 4.4 CHEMBL1963785 CHEMBL291273 CCOCCNc1nc(SC)nc2c1cnn2CC(Cl)c3ccccc3 5.82 CHEMBL962773 CHEMBL296586 Brc1ccc2[nH]c3c(CC(=O)Nc4ccccc34)c2c1 6.8 CHEMBL1963785 CHEMBL298445 Cc1nc(N)sc1c2ccnc(Nc3cccc(c3)[N+](=O)[O-])n2 6.8 CHEMBL939368 CHEMBL306380 Cc1ccc(cc1)c2nn(c3ncnc(N)c23)C(C)(C)C 6.6 CHEMBL1963785 CHEMBL312214 CCCNc1nc(SC)nc2c1cnn2CC(Cl)c3ccccc3 5.32 CHEMBL962773 CHEMBL3288854 CN1CCN(CCC(=O)Nc2c(C)[nH]c(\C=C\3/C(=O)Nc4ccc(F)cc34)c2C)CC1 6.92 CHEMBL3296766 CHEMBL336961 Brc1ccc2[nH]c3c(CC(=O)Nc4cccnc34)c2c1 6.2 CHEMBL1963785 CHEMBL3393071 CC(C)Sc1nc(Nc2cccc(O)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.92 CHEMBL3395760 CHEMBL3393986 Cl.Oc1cccc(Nc2nc(SCCN3CCOCC3)nc4c2cnn4CCc5ccccc5)c1 6.89 CHEMBL3395760 CHEMBL3394082 Cl.CC(Cn1ncc2c(Nc3cccc(O)c3)nc(SCCN4CCOCC4)nc12)c5ccccc5 6.37 CHEMBL3395760 CHEMBL3394083 CSc1nc(Nc2cccc(O)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.82 CHEMBL3395760 CHEMBL3394091 Oc1cccc(Nc2nc(SC3CCCC3)nc4c2cnn4CC(Cl)c5ccccc5)c1 6.82 CHEMBL3395760 CHEMBL3394092 ClC(Cn1ncc2c(Nc3cccc(Br)c3)nc(SCCN4CCOCC4)nc12)c5ccccc5 6.92 CHEMBL3395760 CHEMBL3617732 CCCC(=O)Nc1cccc(Nc2nccc(Nc3cc([nH]n3)C4CC4)n2)c1 6.01 CHEMBL3619920 CHEMBL3617738 O=C(CCCCCC(=O)N1CCC[C@@H]1c2occc2)Nc3cccc(Nc4nccc(Nc5cc([nH]n5)C6CC6)n4)c3 6.14 CHEMBL3619920 CHEMBL3617740 C[C@@H](NC(=O)CCCCCC(=O)Nc1cccc(Nc2nccc(Nc3cc([nH]n3)C4CC4)n2)c1)c5occc5 5.92 CHEMBL3619920 CHEMBL3639839 Cc1ccc(F)cc1c2ccc3cc(NC(=O)c4cccc(F)c4)ncc3c2 7.24 CHEMBL3705971 CHEMBL3639840 Cc1c(F)cncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.7 CHEMBL3705971 CHEMBL3639884 Cc1cnc(CO)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.4 CHEMBL3705971 CHEMBL3639885 Cc1cccc(C)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.69 CHEMBL3705971 CHEMBL3684995 O=C(Nc1cc2ccc(cc2cn1)N3CCCCC3)C4CC4 8.22 CHEMBL3705971 CHEMBL3684996 Clc1ccccc1c2ccc3cc(Nc4ncccn4)ncc3c2 6.86 CHEMBL3705971 CHEMBL3684997 Clc1ccccc1c2ccc3cc(Nc4ccccn4)ncc3c2 8.16 CHEMBL3705971 CHEMBL3684998 CSCNc1cc2ccc(cc2cn1)c3cc(F)ccc3Cl 7.14 CHEMBL3705971 CHEMBL3684999 CNc1cc2ccc(cc2cn1)c3cc(F)ccc3Cl 6.38 CHEMBL3705971 CHEMBL3685000 COc1ccc(Cl)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685001 Cc1ccc(F)cc1c2ccc3cc(N)ncc3c2 6.36 CHEMBL3705971 CHEMBL3685002 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CCC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685003 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CCCC4)ncc3c2 7.92 CHEMBL3705971 CHEMBL3685004 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CCCCC4)ncc3c2 7.41 CHEMBL3705971 CHEMBL3685005 Cc1ccc(F)cc1c2ccc3cc(NC(=O)c4ccccc4)ncc3c2 7.39 CHEMBL3705971 CHEMBL3685006 Cc1ccc(F)cc1c2ccc3cc(NC(=O)c4ccc(F)cc4)ncc3c2 7.59 CHEMBL3705971 CHEMBL3685007 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4(F)CC4)ncc3c2 7.82 CHEMBL3705971 CHEMBL3685008 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4(C)CC4)ncc3c2 7.3 CHEMBL3705971 CHEMBL3685009 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CC4F)ncc3c2 10 CHEMBL3705971 CHEMBL3685010 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CC4(F)F)ncc3c2 9.4 CHEMBL3705971 CHEMBL3685011 Cc1cnc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3685012 Nc1ccc(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685013 O=C(Nc1cc2ccc(cc2cn1)c3cnccc3C#N)C4CC4 9 CHEMBL3705971 CHEMBL3685014 Fc1cnc(C#N)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.05 CHEMBL3705971 CHEMBL3685015 Cc1c(Cl)cccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685016 Cc1cc(F)ccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.52 CHEMBL3705971 CHEMBL3685017 Cc1cc(Cl)ccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685018 COc1ccc(F)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.22 CHEMBL3705971 CHEMBL3685019 CC(C)Oc1ccc(F)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.4 CHEMBL3705971 CHEMBL3685020 Cc1ccncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.52 CHEMBL3705971 CHEMBL3685021 Cn1cc(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3685022 Cc1n[nH]c(C)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3685023 Oc1ccc(Cl)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.4 CHEMBL3705971 CHEMBL3685024 Cc1cc(F)c(F)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.3 CHEMBL3705971 CHEMBL3685025 Cc1ccc(F)cc1c2ccc3cc(\N=C/4\NC(C)(C)CO4)ncc3c2 6.67 CHEMBL3705971 CHEMBL3685026 O=C(Nc1cc2ccc(cc2cn1)N3CCCC3)C4CC4 7.77 CHEMBL3705971 CHEMBL3685027 O=C(Nc1cc2ccc(cc2cn1)C3CCCCC3)C4CC4 8.7 CHEMBL3705971 CHEMBL3685028 CN1CCN(CC1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 6.4 CHEMBL3705971 CHEMBL3685029 O=C(Nc1cc2ccc(cc2cn1)C3CCCC3)C4CC4 8.7 CHEMBL3705971 CHEMBL3685030 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CCOCC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3685031 CN1CCC(CC1)C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 9 CHEMBL3705971 CHEMBL3685032 Cc1ccc(F)cc1c2ccc3cc(NC(=O)c4ccncc4)ncc3c2 8.16 CHEMBL3705971 CHEMBL3685033 Cc1ccc(F)cc1c2ccc3cc(NC(=O)c4ccccc4F)ncc3c2 7.07 CHEMBL3705971 CHEMBL3685034 COc1ccc(cc1)C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 7.28 CHEMBL3705971 CHEMBL3685035 Cc1cccnc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10 CHEMBL3705971 CHEMBL3685036 Cc1ncccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685037 O=C(Nc1cc2ccc(cc2cn1)c3ccc4[nH]ccc4c3)C5CC5 9 CHEMBL3705971 CHEMBL3685038 OC1CCN(CC1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3685039 O=C(Nc1cc2ccc(cc2cn1)N3CCNCC3)C4CC4 6.62 CHEMBL3705971 CHEMBL3685040 CN1C(=O)C=CC=C1c2ccc3cc(NC(=O)C4CC4)ncc3c2 7.8 CHEMBL3705971 CHEMBL3685041 CC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 9.52 CHEMBL3705971 CHEMBL3685042 Cc1ccc(F)cc1c2ccc3cc(NC(=O)CC(F)(F)F)ncc3c2 8.52 CHEMBL3705971 CHEMBL3685043 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C(C)(C)C)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685044 COCC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 9.52 CHEMBL3705971 CHEMBL3685045 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C#N 9.7 CHEMBL3705971 CHEMBL3685046 COc1cccc(C#N)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3685047 O=C(Nc1cc2ccc(cc2cn1)c3ccccn3)C4CC4 8.7 CHEMBL3705971 CHEMBL3685048 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2 10 CHEMBL3705971 CHEMBL3685049 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4C[C@H]4F)ncc3c2 10.05 CHEMBL3705971 CHEMBL3685050 CN(C)CC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 9 CHEMBL3705971 CHEMBL3685051 CCn1nccc1C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 7.47 CHEMBL3705971 CHEMBL3685052 COc1ccccc1C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 6.88 CHEMBL3705971 CHEMBL3685053 COc1cccc(c1)C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 6.44 CHEMBL3705971 CHEMBL3685054 O=C(Nc1cc2ccc(cc2cn1)c3cccc4[nH]ccc34)C5CC5 9.52 CHEMBL3705971 CHEMBL3685055 Fc1cc(C#N)c(cc1F)c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.15 CHEMBL3705971 CHEMBL3685056 Cc1ccc(O)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.7 CHEMBL3705971 CHEMBL3685057 CCC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 9.3 CHEMBL3705971 CHEMBL3685058 CC(C)C(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 8.05 CHEMBL3705971 CHEMBL3685059 O=C(Nc1cc2ccc(cc2cn1)c3cncnc3)C4CC4 8.4 CHEMBL3705971 CHEMBL3685060 Cc1cc(C)c(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.16 CHEMBL3705971 CHEMBL3685061 Cc1nc(cs1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 7.89 CHEMBL3705971 CHEMBL3685062 O=C(Nc1cc2ccc(cc2cn1)c3cc[nH]n3)C4CC4 9.3 CHEMBL3705971 CHEMBL3685063 Cc1ncc(F)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.16 CHEMBL3705971 CHEMBL3685064 CN1C=CC(=O)C(=C1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 7.38 CHEMBL3705971 CHEMBL3685065 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C(F)(F)F)ncc3c2 7.48 CHEMBL3705971 CHEMBL3685066 Fc1ccc(C#N)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.7 CHEMBL3705971 CHEMBL3685067 Clc1ccc(C#N)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.05 CHEMBL3705971 CHEMBL3685068 Fc1ccc(c2ccc3cc(NC(=O)C4CC4)ncc3c2)c(c1)C#N 10.22 CHEMBL3705971 CHEMBL3685069 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C(F)F)ncc3c2 9 CHEMBL3705971 CHEMBL3685070 Cc1ccc(F)cc1c2ccc3cc(NS(=O)(=O)C)ncc3c2 7.57 CHEMBL3705971 CHEMBL3685071 Cc1ccc(F)cc1c2ccc3cc(NS(=O)(=O)C4CC4)ncc3c2 7.38 CHEMBL3705971 CHEMBL3685072 CNC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 10 CHEMBL3705971 CHEMBL3685073 O=C(Nc1cc2ccc(Nc3ccccc3)cc2cn1)C4CC4 9 CHEMBL3705971 CHEMBL3685074 Cc1ncncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.3 CHEMBL3705971 CHEMBL3685075 COc1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.22 CHEMBL3705971 CHEMBL3685076 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(F)(F)F 7.7 CHEMBL3705971 CHEMBL3685077 CN(C)c1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685078 Cc1cnccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685079 CN(C)C(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 8.52 CHEMBL3705971 CHEMBL3685080 Cc1ccnc(C)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.52 CHEMBL3705971 CHEMBL3685081 Cc1ncnc(C)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685082 O=C(Nc1cc2ccc(OC3CCCCC3)cc2cn1)C4CC4 7.57 CHEMBL3705971 CHEMBL3685083 O=C(Nc1cc2ccc(Sc3ccccc3)cc2cn1)C4CC4 7.89 CHEMBL3705971 CHEMBL3685084 Cn1nccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685085 Fc1cncc(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.3 CHEMBL3705971 CHEMBL3685086 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4(O)CC4)ncc3c2 7.38 CHEMBL3705971 CHEMBL3685087 O=C(Nc1cc2ccc(cc2cn1)c3ccc[nH]3)C4CC4 9.16 CHEMBL3705971 CHEMBL3685088 Oc1ccc(C#N)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.7 CHEMBL3705971 CHEMBL3685089 Cc1c(O)cccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.52 CHEMBL3705971 CHEMBL3685090 CC(Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C)C(F)(F)F 7.38 CHEMBL3705971 CHEMBL3685091 Cc1ccc(F)cc1c2ccc3cc(NCC4CC4)ncc3c2 7.38 CHEMBL3705971 CHEMBL3685092 CC(C)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 9.1 CHEMBL3705971 CHEMBL3685093 FC(F)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 8.4 CHEMBL3705971 CHEMBL3685094 Cc1ccc(F)cc1c2ccc3c(Cl)c(N)ncc3c2 7.82 CHEMBL3705971 CHEMBL3685095 Cc1cc(F)c(O)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.52 CHEMBL3705971 CHEMBL3685096 Cc1ccc(CO)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.52 CHEMBL3705971 CHEMBL3685097 Oc1cc(ccc1F)c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.05 CHEMBL3705971 CHEMBL3685098 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)N 9.05 CHEMBL3705971 CHEMBL3685099 CCNC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 9.7 CHEMBL3705971 CHEMBL3685100 Cc1ccc(F)cc1c2ccc3c(Cl)c(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685101 Cc1ccncc1c2ccc3cc(NC(=O)C4CC4F)ncc3c2 10.7 CHEMBL3705971 CHEMBL3685102 Cc1c[nH]nc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10 CHEMBL3705971 CHEMBL3685103 Cc1ccc(F)cc1c2ccc3c(Br)c(NC(=O)C4CC4)ncc3c2 9.05 CHEMBL3705971 CHEMBL3685104 O=C(Nc1cc2ccc(Oc3ccccc3)cc2cn1)C4CC4 8.52 CHEMBL3705971 CHEMBL3685105 Clc1ccccc1Oc2ccc3cc(NC(=O)C4CC4)ncc3c2 8.3 CHEMBL3705971 CHEMBL3685106 Fc1cccc(Oc2ccc3cc(NC(=O)C4CC4)ncc3c2)c1 8.3 CHEMBL3705971 CHEMBL3685107 Clc1cccc(Oc2ccc3cc(NC(=O)C4CC4)ncc3c2)c1 8.1 CHEMBL3705971 CHEMBL3685108 Fc1ccc(Oc2ccc3cc(NC(=O)C4CC4)ncc3c2)cc1 7.7 CHEMBL3705971 CHEMBL3685109 O=C(Nc1cc2ccc(Oc3cccnc3)cc2cn1)C4CC4 8.22 CHEMBL3705971 CHEMBL3685110 COCCNC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 9.7 CHEMBL3705971 CHEMBL3685111 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CCNCC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685112 CN1CCC(C1)C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 8.52 CHEMBL3705971 CHEMBL3685113 CCN1CCC(CC1)C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 8.7 CHEMBL3705971 CHEMBL3685114 CN1CCC(CC1)C(=O)Nc2cc3ccc(cc3cn2)c4cnccc4C 8.7 CHEMBL3705971 CHEMBL3685115 Cc1ccc(F)cc1c2ccc3c(F)c(NC(=O)C4CC4)ncc3c2 9.16 CHEMBL3705971 CHEMBL3685116 CCNC(=O)Nc1ncc2cc(ccc2c1Cl)c3cc(F)ccc3C 7.43 CHEMBL3705971 CHEMBL3685117 CCNC(=O)Nc1ncc2cc(ccc2c1F)c3cc(F)ccc3C 8.4 CHEMBL3705971 CHEMBL3685118 Cc1ccc(F)cc1c2ccc3cc(NC(=O)CC4CC4)ncc3c2 9.05 CHEMBL3705971 CHEMBL3685119 Cc1ccc(F)cc1c2ccc3cc(Nc4cc(CO)ccn4)ncc3c2 9.22 CHEMBL3705971 CHEMBL3685120 O=C(Nc1cc2ccc(cc2cn1)c3cnccn3)C4CC4 7.75 CHEMBL3705971 CHEMBL3685121 Cc1cnc(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 7.38 CHEMBL3705971 CHEMBL3685122 O=C(Nc1cc2ccc(Oc3cncnc3)cc2cn1)C4CC4 7.38 CHEMBL3705971 CHEMBL3685123 CC(C)NC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 9 CHEMBL3705971 CHEMBL3685124 Cc1ccc(F)cc1c2ccc3cc(NC(=O)NC4COC4)ncc3c2 9.7 CHEMBL3705971 CHEMBL3685125 Cc1ccc(F)cc1c2ccc3cc(NC4=CC=CC(=O)N4)ncc3c2 7.68 CHEMBL3705971 CHEMBL3685126 Cc1ncc(cc1F)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.4 CHEMBL3705971 CHEMBL3685127 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(C)(C)O 7.66 CHEMBL3705971 CHEMBL3685128 COc1cccc(Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C)n1 8.4 CHEMBL3705971 CHEMBL3685129 CN1CCN(CC1)C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 8.4 CHEMBL3705971 CHEMBL3685130 Cc1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685131 Cc1cc(ccn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 7.38 CHEMBL3705971 CHEMBL3685132 Cn1ccc(Oc2ccc3cc(NC(=O)C4CC4)ncc3c2)n1 8.16 CHEMBL3705971 CHEMBL3685133 Cc1ccc(F)cc1c2ccc3cc(NC(=O)NC4CCOCC4)ncc3c2 9.22 CHEMBL3705971 CHEMBL3685134 O=C(Nc1cc2ccc(cc2cn1)c3cccc4[nH]ncc34)C5CC5 10.4 CHEMBL3705971 CHEMBL3685135 O=C(Nc1cc2ccc(cc2cn1)c3ccc4cn[nH]c4c3)C5CC5 7.96 CHEMBL3705971 CHEMBL3685136 O=C(Nc1cc2ccc(cc2cn1)c3ccnnc3)C4CC4 7.47 CHEMBL3705971 CHEMBL3685137 Cc1nccnc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685138 CC(C)Nc1ccc2cc(NC(=O)C3CC3)ncc2c1 9.16 CHEMBL3705971 CHEMBL3685139 CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(c3)c4ccc5cc(NC(=O)C6CC6)ncc5c4)CC1 9.52 CHEMBL3705971 CHEMBL3685140 CN1CCN(Cc2ccc(cc2Cl)C(=O)Nc3ccc(C)c(c3)c4ccc5cc(NC(=O)C6CC6)ncc5c4)CC1 9.16 CHEMBL3705971 CHEMBL3685141 CC(C)COc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.92 CHEMBL3705971 CHEMBL3685142 CC(C)OC(=O)Nc1cc2ccc(cc2cn1)c3cc(F)ccc3C 8.3 CHEMBL3705971 CHEMBL3685143 Nc1cncc(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.4 CHEMBL3705971 CHEMBL3685144 Nc1cc(ccn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.16 CHEMBL3705971 CHEMBL3685145 CC(=Cc1ccc2cc(NC(=O)C3CC3)ncc2c1)C 8.52 CHEMBL3705971 CHEMBL3685146 Cc1cc(Cl)ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10 CHEMBL3705971 CHEMBL3685147 Clc1ccncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.15 CHEMBL3705971 CHEMBL3685148 CC(C)Cc1ccc2cc(NC(=O)C3CC3)ncc2c1 9 CHEMBL3705971 CHEMBL3685149 Cn1ncc2c(cccc12)c3ccc4cc(NC(=O)C5CC5)ncc4c3 8.05 CHEMBL3705971 CHEMBL3685150 O=C(Nc1cc2ccc(cc2cn1)c3cccc4NC(=O)Cc34)C5CC5 9.22 CHEMBL3705971 CHEMBL3685151 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CC4c5ccccc5)ncc3c2 8.16 CHEMBL3705971 CHEMBL3685152 Cc1cc(CO)cc(Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C)n1 8.3 CHEMBL3705971 CHEMBL3685153 Cc1cc(cc(Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C)n1)C(C)(C)O 8.3 CHEMBL3705971 CHEMBL3685154 Cc1cc(N)ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.05 CHEMBL3705971 CHEMBL3685155 Cc1ccncc1c2ccc3cc(Nc4cc(CO)ccn4)ncc3c2 10 CHEMBL3705971 CHEMBL3685156 Cc1ncc(CO)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3685157 COc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.52 CHEMBL3705971 CHEMBL3685158 C[C@@H](CO)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 8.7 CHEMBL3705971 CHEMBL3685159 CC(C)(CO)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.96 CHEMBL3705971 CHEMBL3685160 CC(O)c1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685161 OCc1cccc(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3685162 OCc1ccc(Cl)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.7 CHEMBL3705971 CHEMBL3685163 OCc1ccc(F)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.1 CHEMBL3705971 CHEMBL3685164 CCOc1ccc2cc(NC(=O)C3CC3)ncc2c1 8.16 CHEMBL3705971 CHEMBL3685165 OCCOc1ccc2cc(NC(=O)C3CC3)ncc2c1 8.22 CHEMBL3705971 CHEMBL3685166 CC(CO)Cc1ccc2cc(NC(=O)C3CC3)ncc2c1 9.1 CHEMBL3705971 CHEMBL3685167 C[C@H](CO)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.96 CHEMBL3705971 CHEMBL3685168 COC[C@H](C)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 8.1 CHEMBL3705971 CHEMBL3685169 C[C@H]1CC1C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 9.1 CHEMBL3705971 CHEMBL3685170 C[C@@H]1CC1C(=O)Nc2cc3ccc(cc3cn2)c4cc(F)ccc4C 8.4 CHEMBL3705971 CHEMBL3685171 Cc1ccc(NC(=O)c2cnn(C)c2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9 CHEMBL3705971 CHEMBL3685172 OCc1ncccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10 CHEMBL3705971 CHEMBL3685173 Cc1cc(ccn1)C(=O)Nc2ccc(C)c(c2)c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.1 CHEMBL3705971 CHEMBL3685174 Cc1ccc(NC(=O)C2CCOCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.7 CHEMBL3705971 CHEMBL3685175 Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 8.7 CHEMBL3705971 CHEMBL3685176 CN1CCC(CC1)C(=O)Nc2ccc(C)c(c2)c3ccc4cc(NC(=O)C5CC5)ncc4c3 8.16 CHEMBL3705971 CHEMBL3685177 CN(C)Cc1ccc(cc1)C(=O)Nc2ccc(C)c(c2)c3ccc4cc(NC(=O)C5CC5)ncc4c3 10 CHEMBL3705971 CHEMBL3685178 Cc1c(N)cncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.05 CHEMBL3705971 CHEMBL3685179 Cc1c(O)cncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.4 CHEMBL3705971 CHEMBL3685180 Cc1cc(CO)ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.7 CHEMBL3705971 CHEMBL3685181 Cc1ccnc(CO)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.15 CHEMBL3705971 CHEMBL3685182 OC1CCN(C1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3685183 NCc1cccc(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 7.39 CHEMBL3705971 CHEMBL3685184 Cc1c(CO)cncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.7 CHEMBL3705971 CHEMBL3685185 CC(C)(C)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.89 CHEMBL3705971 CHEMBL3685186 CC(N(C)C)c1ccc(cc1)C(=O)Nc2ccc(C)c(c2)c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.52 CHEMBL3705971 CHEMBL3685187 Cc1ccncc1c2ccc3cc(Nc4cccc(CO)n4)ncc3c2 9.7 CHEMBL3705971 CHEMBL3685188 COC[C@@H](C)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.57 CHEMBL3705971 CHEMBL3685189 C[C@H](CCO)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.64 CHEMBL3705971 CHEMBL3685190 O=C(Nc1cc2ccc(OC3CCC3)cc2cn1)C4CC4 8.16 CHEMBL3705971 CHEMBL3685191 OCc1ccncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.4 CHEMBL3705971 CHEMBL3685192 C[C@H](CNC(=O)c1ccc(CN2CCN(C)CC2)cc1)Cc3ccc4cc(NC(=O)C5CC5)ncc4c3 7.38 CHEMBL3705971 CHEMBL3685193 C[C@@H](CNC(=O)c1ccc(CN2CCN(C)CC2)cc1)Cc3ccc4cc(NC(=O)C5CC5)ncc4c3 8.3 CHEMBL3705971 CHEMBL3685194 C[C@@H](CCO)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 8.7 CHEMBL3705971 CHEMBL3685195 Clc1ccc(NC(=O)C2CCOCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 8.7 CHEMBL3705971 CHEMBL3685196 Fc1ccc(NC(=O)C2CCOCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 7.57 CHEMBL3705971 CHEMBL3685197 Cc1ccccc1c2ccc3cnc(NC(=O)C4CC4)cc3c2 8.4 CHEMBL3705971 CHEMBL3685198 Cc1ccc(NC(=O)[C@H]2CCCO2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.22 CHEMBL3705971 CHEMBL3685199 Cc1ccc(NC(=O)[C@@H]2CCCO2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.4 CHEMBL3705971 CHEMBL3689538 CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(F)c(c3)c4ccc5cc(NC(=O)C6CC6)ncc5c4)CC1 9.3 CHEMBL3705971 CHEMBL3689539 CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(Cl)c(c3)c4ccc5cc(NC(=O)C6CC6)ncc5c4)CC1 9.4 CHEMBL3705971 CHEMBL3689540 Cc1ccc(NC(=O)C2CCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.52 CHEMBL3705971 CHEMBL3689541 C[C@H](CO)Cc1ccc2cc(NC(=O)C3CC3)ncc2c1 9.3 CHEMBL3705971 CHEMBL3689542 C[C@@H](CO)Cc1ccc2cc(NC(=O)C3CC3)ncc2c1 9.3 CHEMBL3705971 CHEMBL3689543 Cc1ccc(NC(=O)C2CCOC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.22 CHEMBL3705971 CHEMBL3689544 Cc1cc(ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(C)(C)O 10 CHEMBL3705971 CHEMBL3689545 CNC(=O)c1cc(C)c(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8 CHEMBL3705971 CHEMBL3689546 Cc1ccc(NC(=O)N2CCOCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.4 CHEMBL3705971 CHEMBL3689547 CN1CCOC(C1)C(=O)Nc2ccc(C)c(c2)c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.7 CHEMBL3705971 CHEMBL3689548 Cc1ccc(NC(=O)N2CCCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 10.05 CHEMBL3705971 CHEMBL3689549 Cc1ccc(NC(=O)N2CCOC(CO)C2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.3 CHEMBL3705971 CHEMBL3689550 CC(C)Sc1ccc2cc(NC(=O)C3CC3)ncc2c1 9 CHEMBL3705971 CHEMBL3689551 CC(C)[S+]([O-])c1ccc2cc(NC(=O)C3CC3)ncc2c1 9 CHEMBL3705971 CHEMBL3689552 CC(C)S(=O)(=O)c1ccc2cc(NC(=O)C3CC3)ncc2c1 9 CHEMBL3705971 CHEMBL3689553 FC(F)(F)c1ccncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.52 CHEMBL3705971 CHEMBL3689554 Cc1c(F)c(CO)ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.7 CHEMBL3705971 CHEMBL3689555 COc1cc(C)c(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3689556 O[C@H]1COCC1Oc2ccc3cc(NC(=O)C4CC4)ncc3c2 8.3 CHEMBL3705971 CHEMBL3689557 O[C@@H]1COCC1Oc2ccc3cc(NC(=O)C4CC4)ncc3c2 7.66 CHEMBL3705971 CHEMBL3689558 CN1CCCC1c2ccc(cc2)C(=O)Nc3ccc(C)c(c3)c4ccc5cc(NC(=O)C6CC6)ncc5c4 9.52 CHEMBL3705971 CHEMBL3689559 CN1CCC(C1)c2ccc(cc2)C(=O)Nc3ccc(C)c(c3)c4ccc5cc(NC(=O)C6CC6)ncc5c4 9.16 CHEMBL3705971 CHEMBL3689560 Cc1nc(N)ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3689561 Cc1c(NC(=O)C2CCOCC2)cncc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 7.38 CHEMBL3705971 CHEMBL3689562 Cc1ccncc1c2ccc3cc(N)ncc3c2 7.44 CHEMBL3705971 CHEMBL3689563 CC[C@@H](O)c1cc(C)c(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 10 CHEMBL3705971 CHEMBL3689564 CC[C@H](O)c1cc(C)c(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 10 CHEMBL3705971 CHEMBL3689565 Cc1ccc(NC(=O)C2COCCO2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.7 CHEMBL3705971 CHEMBL3689566 Cc1ncc(N)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.4 CHEMBL3705971 CHEMBL3689567 C[C@@H](O)c1cc(C)c(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.3 CHEMBL3705971 CHEMBL3689568 C[C@H](O)c1cc(C)c(cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.3 CHEMBL3705971 CHEMBL3689569 O[C@H]1CCCC1Oc2ccc3cc(NC(=O)C4CC4)ncc3c2 7.4 CHEMBL3705971 CHEMBL3689570 O[C@@H]1CCCCC1Oc2ccc3cc(NC(=O)C4CC4)ncc3c2 8.05 CHEMBL3705971 CHEMBL3689571 O[C@H]1CCCCC1Oc2ccc3cc(NC(=O)C4CC4)ncc3c2 8.05 CHEMBL3705971 CHEMBL3689572 Cc1ncc(NC(=O)C2CCOCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 8.05 CHEMBL3705971 CHEMBL3689573 OCCNc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.77 CHEMBL3705971 CHEMBL3689574 Cc1ccc2[nH]ncc2c1c3ccc4cc(NC(=O)C5CC5)ncc4c3 10.52 CHEMBL3705971 CHEMBL3689575 Cc1ncc2[nH]ncc2c1c3ccc4cc(NC(=O)C5CC5)ncc4c3 10.4 CHEMBL3705971 CHEMBL3689576 CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(c3)c4ccc5cc(N)ncc5c4)CC1 9.4 CHEMBL3705971 CHEMBL3689577 Cc1ccncc1c2ccc3cc(NC(=O)[C@H]4C[C@H]4F)ncc3c2 10.22 CHEMBL3705971 CHEMBL3689578 Cc1ccncc1c2ccc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c2 10.3 CHEMBL3705971 CHEMBL3689579 Cc1ccncc1c2ccc3cc(NC(=O)C4C5COCC45)ncc3c2 9.4 CHEMBL3705971 CHEMBL3689580 Cc1cnc(F)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3689581 Cc1cc(c(C)cn1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 7.7 CHEMBL3705971 CHEMBL3689582 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5CCOCC5 9.1 CHEMBL3705971 CHEMBL3689583 O=C(Nc1cc2ccc(cc2cn1)c3cncc4[nH]ncc34)C5CC5 9 CHEMBL3705971 CHEMBL3689584 CN(C)Cc1ccc(cc1)C2CC2C(=O)Nc3cc4ccc(cc4cn3)c5cc(F)ccc5C 9.7 CHEMBL3705971 CHEMBL3689585 COCC(=O)Nc1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3689586 CO[C@H](C)C(=O)Nc1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.4 CHEMBL3705971 CHEMBL3689587 CO[C@@H](C)C(=O)Nc1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3689588 O[C@@H]1CCCC1Oc2ccc3cc(NC(=O)C4CC4)ncc3c2 9.7 CHEMBL3705971 CHEMBL3689589 O=C(Nc1cc2ccc(cc2cn1)c3cccc4[nH]cnc34)C5CC5 9 CHEMBL3705971 CHEMBL3689590 COC(C)(C)C(=O)Nc1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3689591 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5COC5 9 CHEMBL3705971 CHEMBL3689592 CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc3cnc(C)c(c3)c4ccc5cc(NC(=O)C6CC6)ncc5c4)CC1 9.7 CHEMBL3705971 CHEMBL3689593 CCS(=O)(=O)Nc1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.52 CHEMBL3705971 CHEMBL3689594 Cc1ccc(NC(=O)C2(O)CCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.52 CHEMBL3705971 CHEMBL3689595 Cc1ccc(F)cc1c2ccc3cc(ncc3c2)C(=O)NC4CC4 7.38 CHEMBL3705971 CHEMBL3689596 Cc1cc(ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)[C@H](O)C(F)(F)F 10.52 CHEMBL3705971 CHEMBL3689597 Cc1cc(ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)[C@@H](O)C(F)(F)F 9.7 CHEMBL3705971 CHEMBL3689598 COc1ccncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.7 CHEMBL3705971 CHEMBL3689599 Cc1ccc(NS(=O)(=O)C2CCCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 8 CHEMBL3705971 CHEMBL3689600 Cc1ccc(NC(=O)N2CCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.52 CHEMBL3705971 CHEMBL3689601 Cc1ccc(NC(=O)N2CCS(=O)(=O)CC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 8.7 CHEMBL3705971 CHEMBL3689602 Cc1ccc(NC(=O)N2CCC[C@@H]2CO)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.7 CHEMBL3705971 CHEMBL3689603 Cc1ccc(NC(=O)N2CCC[C@H]2CO)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.7 CHEMBL3705971 CHEMBL3689604 Cc1ccc(NC(=O)N2CC[C@@H](O)C2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.4 CHEMBL3705971 CHEMBL3689605 Cc1ccc(NC(=O)N2CC[C@H](O)C2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.22 CHEMBL3705971 CHEMBL3689606 Cc1ncc(O)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10 CHEMBL3705971 CHEMBL3689607 Cc1ccncc1c2ccc3cc(NC(=O)C4CC4(F)F)ncc3c2 10 CHEMBL3705971 CHEMBL3689608 Cc1ccncc1c2ccc3cc(NC(=O)C4C[C@H]4F)ncc3c2 10.52 CHEMBL3705971 CHEMBL3689609 Cc1ccncc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2 10.15 CHEMBL3705971 CHEMBL3689610 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5(C)CCC5 9.52 CHEMBL3705971 CHEMBL3689611 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5(C)CCS(=O)(=O)C5 9 CHEMBL3705971 CHEMBL3689612 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5CCCC5 9.3 CHEMBL3705971 CHEMBL3689613 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5CCOC5 9.05 CHEMBL3705971 CHEMBL3689614 COCCNC(=O)c1ccc(C)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3689615 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC(C)(C)CO 7.96 CHEMBL3705971 CHEMBL3689616 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)Nc5cnn(C)c5 9.22 CHEMBL3705971 CHEMBL3689617 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)N5CCOCC5 7.4 CHEMBL3705971 CHEMBL3689618 Cc1cncc(C)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9 CHEMBL3705971 CHEMBL3689619 Cc1ccncc1c2ccc3c(C#N)c(N)ncc3c2 8.3 CHEMBL3705971 CHEMBL3689620 Cc1ccncc1c2ccc3c(C#N)c(NC(=O)C4CC4)ncc3c2 9.16 CHEMBL3705971 CHEMBL3689621 Cc1cc(ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)O 8.52 CHEMBL3705971 CHEMBL3689622 Cc1ccc(F)cc1c2ccc3cc(ncc3c2)C(=O)NC4CCC4 7.38 CHEMBL3705971 CHEMBL3689623 Cc1c(F)cc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5COC5 9 CHEMBL3705971 CHEMBL3689624 Cc1ccc(C(=O)NC2COC2)c(F)c1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9 CHEMBL3705971 CHEMBL3689625 Cc1ccc(C(=O)NC2CCOCC2)c(F)c1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9 CHEMBL3705971 CHEMBL3689626 Cc1c(F)cc(NC(=O)C2CCC2)cc1c3ccc4cc(NC(=O)C5CC5)ncc4c3 8.7 CHEMBL3705971 CHEMBL3689627 Cc1cc(ccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(C)(C)O 8.16 CHEMBL3705971 CHEMBL3689628 Cc1ccc(NC(=O)C2CCC2)c(F)c1c3ccc4cc(NC(=O)C5CC5)ncc4c3 9.7 CHEMBL3705971 CHEMBL3689629 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5(C)COC5 8.7 CHEMBL3705971 CHEMBL3689630 Cc1ccc(cc1c2ccc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c2)C(=O)NC5(C)COC5 8 CHEMBL3705971 CHEMBL3689631 Cc1cc(ncc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2)[C@H](O)C(F)(F)F 10.7 CHEMBL3705971 CHEMBL3689632 Cc1cc(ncc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2)[C@@H](O)C(F)(F)F 10 CHEMBL3705971 CHEMBL3689633 CNC(=O)Nc1cc2ccc(cc2cn1)c3cnccc3C 10 CHEMBL3705971 CHEMBL3689634 Fc1ccc(Cl)c(c1)c2cc3cnc(NC(=O)C4CC4)cc3cn2 9.4 CHEMBL3705971 CHEMBL3689635 Clc1ccccc1c2cc3cnc(NC(=O)C4CC4)cc3c(Cl)n2 9.1 CHEMBL3705971 CHEMBL3689636 Cc1nc(cc2cnc(NC(=O)C3CC3)cc12)c4ccccc4Cl 10 CHEMBL3705971 CHEMBL3689637 Clc1ccccc1c2cc3cnc(NC(=O)C4CC4)cc3cn2 9.52 CHEMBL3705971 CHEMBL3689638 Oc1c(ncc2cc(NC(=O)C3CC3)ncc12)c4ccccc4Cl 7.7 CHEMBL3705971 CHEMBL3689639 Clc1ccccc1C2=Cc3cnc(NC(=O)C4CC4)cc3C(=O)N2 8.3 CHEMBL3705971 CHEMBL3689640 [O-][n+]1cc2cc(NC(=O)C3CC3)ncc2cc1c4ccccc4Cl 9.1 CHEMBL3705971 CHEMBL3689641 COc1nc(cc2cnc(NC(=O)C3CC3)cc12)c4ccccc4Cl 8.7 CHEMBL3705971 CHEMBL3689642 CCc1nc(cc2cnc(NC(=O)C3CC3)cc12)c4ccccc4Cl 9.52 CHEMBL3705971 CHEMBL3689643 Clc1ccccc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)C5CC5 8.7 CHEMBL3705971 CHEMBL3689644 O=C(Nc1cc2cnc(cc2cn1)C3CCCCC3)C4CC4 8.7 CHEMBL3705971 CHEMBL3689645 Cc1ccncc1c2cc3cnc(NC(=O)C4CC4)cc3cn2 9.52 CHEMBL3705971 CHEMBL3689646 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3cn2 10 CHEMBL3705971 CHEMBL3689647 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(C)[n+]2[O-] 9.52 CHEMBL3705971 CHEMBL3689648 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c[n+]2[O-] 9.4 CHEMBL3705971 CHEMBL3689649 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(C)n2 10.1 CHEMBL3705971 CHEMBL3689650 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)C#N 9 CHEMBL3705971 CHEMBL3689651 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)N5CCCCC5 8.52 CHEMBL3705971 CHEMBL3689652 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(OC5CCCC5)n2 8.4 CHEMBL3705971 CHEMBL3689653 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(CO)n2 9.7 CHEMBL3705971 CHEMBL3689654 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(Oc5ccccc5)n2 7.92 CHEMBL3705971 CHEMBL3689655 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)c5cccnc5 9.7 CHEMBL3705971 CHEMBL3689656 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(Nc5ccccc5)n2 7.96 CHEMBL3705971 CHEMBL3689657 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(NC5CCCC5)n2 8.3 CHEMBL3705971 CHEMBL3689658 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(CF)n2 9.7 CHEMBL3705971 CHEMBL3689659 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)c5ccnn5C 9.52 CHEMBL3705971 CHEMBL3689660 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)S(=O)(=O)C 9.52 CHEMBL3705971 CHEMBL3689661 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)c5ccccc5 9.4 CHEMBL3705971 CHEMBL3689662 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)c5sc(C)nc5C 9.52 CHEMBL3705971 CHEMBL3689663 Cc1ccncc1c2nc(cc3cnc(NC(=O)C4CC4)cc23)c5cc(F)ccc5C 9 CHEMBL3705971 CHEMBL3689664 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)c5ccncc5 9.7 CHEMBL3705971 CHEMBL3689665 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)c5cc[nH]n5 9.7 CHEMBL3705971 CHEMBL3689666 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)c5cnn(C)c5 10 CHEMBL3705971 CHEMBL3689667 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)c5cn[nH]c5 10 CHEMBL3705971 CHEMBL3689668 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)C(C)(C)O 9.7 CHEMBL3705971 CHEMBL3689669 Cc1c2cc(NC(=O)C3CC3)ncc2cc(c4ccccc4Cl)[n+]1[O-] 9 CHEMBL3705971 CHEMBL3689670 Cc1ccc(CO)cc1c2cc3cnc(NC(=O)C4CC4)cc3cn2 10 CHEMBL3705971 CHEMBL3689671 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(OC5CCNCC5)n2 9.16 CHEMBL3705971 CHEMBL3689672 CN(C)Cc1nc(cc2cnc(NC(=O)C3CC3)cc12)c4cc(F)ccc4C 8 CHEMBL3705971 CHEMBL3689673 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)N5CCNCC5 9 CHEMBL3705971 CHEMBL3689674 CNCc1nc(cc2cnc(NC(=O)C3CC3)cc12)c4cc(F)ccc4C 8.3 CHEMBL3705971 CHEMBL3689675 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(OC5CCNC5)n2 8.7 CHEMBL3705971 CHEMBL3689676 Cc1ccc(F)cc1c2cc3cnc(NC(=O)C4CC4)cc3c(n2)C5CCOC5 9.4 CHEMBL3705971 CHEMBL3689677 Cc1ccncc1c2cc3cnc(NC(=O)[C@@H]4C[C@@H]4F)cc3cn2 9.4 CHEMBL3705971 CHEMBL3689678 Cc1ccc2[nH]ncc2c1c3cc4cnc(NC(=O)[C@@H]5C[C@@H]5F)cc4cn3 10.7 CHEMBL3705971 CHEMBL3689679 Cc1ccc(cc1c2cc3cnc(NC(=O)[C@@H]4C[C@@H]4F)cc3cn2)C(=O)NC5(C)COC5 7.38 CHEMBL3705971 CHEMBL3689680 Fc1ccc(Cl)c(c1)c2cnc3cc(NC(=O)C4CC4)ncc3c2 9.52 CHEMBL3705971 CHEMBL3689681 CCc1nc2cc(NC(=O)C3CC3)ncc2cc1c4ccccc4Cl 7.96 CHEMBL3705971 CHEMBL3689682 Clc1cccc(Cl)c1c2ccc3cc(NC(=O)C4CC4)ncc3n2 7.82 CHEMBL3705971 CHEMBL3689683 OCc1cccc(Nc2cc3ccc(nc3cn2)c4ccccc4Cl)c1 6.67 CHEMBL3705971 CHEMBL3689684 Clc1ccccc1c2ccc3cc(NC(=O)C4CC4)ncc3n2 8.52 CHEMBL3705971 CHEMBL3689685 Cc1cc2cc(NC(=O)C3CC3)ncc2nc1c4cc(F)ccc4Cl 7.77 CHEMBL3705971 CHEMBL3689686 Cc1ccc(F)cc1c2cc(C)c3cc(NC(=O)C4CC4)ncc3n2 7.72 CHEMBL3705971 CHEMBL3689687 Cc1ccc(F)cc1c2cc(O)c3cc(NC(=O)C4CC4)ncc3n2 8.1 CHEMBL3705971 CHEMBL3689688 OC1(CCCCC1)c2ccc3cc(NC(=O)C4CC4)ncc3n2 7.89 CHEMBL3705971 CHEMBL3689689 Oc1cc(nc2cnc(NC(=O)C3CC3)cc12)c4ccccc4Cl 8.22 CHEMBL3705971 CHEMBL3689690 OC1(CCCC1)c2ccc3cc(NC(=O)C4CC4)ncc3n2 8.16 CHEMBL3705971 CHEMBL3689691 Cc1nc(Cl)ncc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.1 CHEMBL3705971 CHEMBL3689692 Cc1ccncc1c2ccc3cc(NC(=O)C4CCO4)ncc3c2 8.92 CHEMBL3705971 CHEMBL3689693 Brc1ccc2cc(NC(=O)C3CC3)ncc2c1 7.6 CHEMBL3705971 CHEMBL3689694 Fc1cc(F)c(c(Cl)c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.63 CHEMBL3705971 CHEMBL3689695 Fc1ccc(F)c(c1Cl)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.79 CHEMBL3705971 CHEMBL3689696 Cc1cccc(F)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.15 CHEMBL3705971 CHEMBL3689697 Cc1cccc(Cl)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.8 CHEMBL3705971 CHEMBL3689698 Fc1ccc(F)c(c1)c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.46 CHEMBL3705971 CHEMBL3689699 Fc1cccc(F)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.76 CHEMBL3705971 CHEMBL3689700 Cc1ccc(F)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.94 CHEMBL3705971 CHEMBL3689701 Cc1ccc(Cl)cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.17 CHEMBL3705971 CHEMBL3689702 Clc1cnccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 8.86 CHEMBL3705971 CHEMBL3689703 O=C(Nc1cc2ccc(cc2cn1)c3ccncc3)C4CC4 8.25 CHEMBL3705971 CHEMBL3689704 O=C(Nc1cc2ccc(cc2cn1)c3cccnc3)C4CC4 9.15 CHEMBL3705971 CHEMBL3689705 FC(F)(F)c1cccc(Cl)c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 7.71 CHEMBL3705971 CHEMBL3689706 O=C(Nc1cc2ccc(cc2cn1)c3ccccc3C#N)C4CC4 9.76 CHEMBL3705971 CHEMBL3689707 Clc1ccccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.51 CHEMBL3705971 CHEMBL3689708 Fc1ccccc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.26 CHEMBL3705971 CHEMBL3689709 CN1CCN(CC1)c2nccc(Nc3cc4ccc(cc4cn3)c5c(Cl)cccc5Cl)n2 8.62 CHEMBL3705971 CHEMBL3689710 Clc1cccc(Cl)c1c2ccc3cc(Nc4ccnc(n4)N5CCOCC5)ncc3c2 8.99 CHEMBL3705971 CHEMBL3689711 CCc1cc(Nc2cc3ccc(cc3cn2)c4c(Cl)cccc4Cl)nc(n1)N5CCOCC5 8.3 CHEMBL3705971 CHEMBL3689712 CCCS(=O)(=O)Nc1ccc(F)c(c1F)c2ccc3cc(NC(=O)C)ncc3c2 7.66 CHEMBL3705971 CHEMBL3689713 Cc1c(Cl)c(ncc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2)[C@@H](O)C(F)(F)F 10.08 CHEMBL3705971 CHEMBL3689714 Cc1c(Cl)c(ncc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2)[C@H](O)C(F)(F)F 8.7 CHEMBL3705971 CHEMBL3689715 Cc1ccncc1c2cc3cnc(NC(=O)C4CC4F)cc3cn2 9.2 CHEMBL3705971 CHEMBL3689716 CC1CC(C)N1c2ccc3cc(NC(=O)C4CC4F)ncc3c2 7.38 CHEMBL3705971 CHEMBL3689717 Cc1c(F)cncc1c2cc3cnc(NC(=O)C4CC4F)cc3c[n+]2[O-] 8.98 CHEMBL3705971 CHEMBL3689718 Cc1c(F)cncc1c2cc3cnc(NC(=O)[C@@H]4C[C@@H]4F)cc3cn2 9.78 CHEMBL3705971 CHEMBL3689719 O=C(Nc1cc2ccc(cc2cn1)c3cccc4[nH]nnc34)C5CC5 10.14 CHEMBL3705971 CHEMBL3689720 Fc1cc(c2ccc3cc(NC(=O)C4CC4)ncc3c2)c5cn[nH]c5c1 9.8 CHEMBL3705971 CHEMBL3689721 Cc1c(F)c(ncc1c2ccc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c2)C(C)(C)O 9.57 CHEMBL3705971 CHEMBL3689722 Cc1c(F)cncc1c2ccc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c2 10.73 CHEMBL3705971 CHEMBL3689723 Cc1ccc[n+]([O-])c1c2ccc3cc(NC(=O)C4CC4)ncc3c2 10.05 CHEMBL3705971 CHEMBL3689724 C[S+]([O-])c1cc(C)c(cn1)c2ccc3cc(NC(=O)C4CC4F)ncc3c2 7.6 CHEMBL3705971 CHEMBL3689725 Cc1cc(ncc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2)[C@@H](N)C(F)(F)F 8 CHEMBL3705971 CHEMBL3689726 Cc1cc(ncc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2)[C@H](N)C(F)(F)F 8.76 CHEMBL3705971 CHEMBL3689727 CCO[C@@H]1CC1C(=O)Nc2cc3ccc(cc3cn2)c4cnccc4C 9.35 CHEMBL3705971 CHEMBL3689728 CCO[C@H]1CC1C(=O)Nc2cc3ccc(cc3cn2)c4cnccc4C 9.35 CHEMBL3705971 CHEMBL3689729 C[C@@H](O)c1nccc(C)c1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2 9.1 CHEMBL3705971 CHEMBL3689730 Cc1ccnc([C@@H](O)C(F)(F)F)c1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2 9.58 CHEMBL3705971 CHEMBL3689731 Cc1ccnc([C@H](O)C(F)(F)F)c1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2 9.58 CHEMBL3705971 CHEMBL3689732 C[C@H](O)c1nccc(C)c1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2 9.1 CHEMBL3705971 CHEMBL3689733 CC(C)C(=O)Nc1cc2ccc(cc2cn1)c3cnc(cc3C)[C@H](O)C(F)(F)F 8.46 CHEMBL3705971 CHEMBL3689734 CC(C)C(=O)Nc1cc2ccc(cc2cn1)c3cnc(cc3C)[C@@H](O)C(F)(F)F 7.38 CHEMBL3705971 CHEMBL3689735 Cc1cc(ncc1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2)C(O)C(F)F 7.48 CHEMBL3705971 CHEMBL3689736 C[C@@H]1CCC(=O)N1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2 10.1 CHEMBL3705971 CHEMBL3689737 C[C@H]1CCC(=O)N1c2ccc3cc(NC(=O)C4C[C@@H]4F)ncc3c2 8.47 CHEMBL3705971 CHEMBL3689738 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5CC(F)(F)C5 9.15 CHEMBL3705971 CHEMBL3689739 Cc1cc(ncc1c2ccc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c2)C(C)(C)O 8.68 CHEMBL3705971 CHEMBL3689740 Cc1cc(ncc1c2cc3cnc(NC(=O)[C@@H]4C[C@@H]4F)cc3cn2)C(C)(C)O 9.66 CHEMBL3705971 CHEMBL3689741 Cc1cc(ncc1c2cc3cnc(NC(=O)C4C[C@@H]4F)cc3cn2)[C@H](O)C(F)(F)F 8.59 CHEMBL3705971 CHEMBL3689742 Cc1cc(ncc1c2cc3cnc(NC(=O)C4C[C@@H]4F)cc3cn2)[C@@H](O)C(F)(F)F 8.77 CHEMBL3705971 CHEMBL3689743 Cc1cc[n+]([O-])cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2 9.78 CHEMBL3705971 CHEMBL3689744 Cc1ccncc1c2cc3c[n+]([O-])c(NC(=O)[C@@H]4C[C@@H]4F)cc3cn2 7.38 CHEMBL3705971 CHEMBL3689745 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5(CO)CCC5 9.23 CHEMBL3705971 CHEMBL3689746 Cc1ccnc(CO)c1c2ccc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c2 9.71 CHEMBL3705971 CHEMBL3689747 F[C@H]1C[C@H]1C(=O)Nc2cc3cnc(cc3cn2)c4ccccc4OC(F)(F)F 7.66 CHEMBL3705971 CHEMBL3689748 Cc1ccc2[nH]ncc2c1c3ccc4cc(NC(=O)[C@@H]5C[C@@H]5F)ncc4c3 8.3 CHEMBL3705971 CHEMBL3689749 Cc1ccc(cc1c2ccc3cc(NC(=O)C4CC4)ncc3c2)C(=O)NC5CCC5 9.38 CHEMBL3705971 CHEMBL3689750 Cc1ccc(cc1c2ccc3cc(N)ncc3c2)C(=O)NC4(C)CCC4 8.11 CHEMBL3705971 CHEMBL3689751 Cc1ccc(cc1c2ccc3cc(N)ncc3c2)C(=O)NC4(C)COC4 7.38 CHEMBL3705971 CHEMBL3689752 Cc1ncc(cc1c2ccc3cc(N)ncc3c2)C(=O)NC4CCC4 7.62 CHEMBL3705971 CHEMBL3689753 Cc1ncc(cc1c2ccc3cc(N)ncc3c2)C(=O)NC4(C)CCC4 7.38 CHEMBL3705971 CHEMBL3689754 Cc1ccc(C(=O)NC2(C)COC2)c(F)c1c3ccc4cc(N)ncc4c3 7.38 CHEMBL3705971 CHEMBL3689755 Cc1ccc(cc1c2ccc3c(Cl)c(N)ncc3c2)C(=O)NC4(C)CCC4 7.48 CHEMBL3705971 CHEMBL371206 Cc1cc(C)cc(NC(=O)Nc2ccc(cc2)c3c(C)sc4ncnc(N)c34)c1 6.7 CHEMBL1963785 CHEMBL373798 Nc1n[nH]c2cccc(c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 6.5 CHEMBL1963785 CHEMBL376993 COc1cc(SC)ccc1C(=O)Nc2nnc(CCc3ccccc3)s2 5.7 CHEMBL859157 CHEMBL378175 Ic1ccc(cc1)N2NC(=O)\C(=C\c3ccc(cc3)N4CCOCC4)\C2=O 4.7 CHEMBL859157 CHEMBL379308 Brc1cc2OCOc2cc1\C=C/3\C(=O)NN(C3=O)c4ccc(I)cc4 5.6 CHEMBL859157 CHEMBL379975 Oc1ccc2[nH]c3cc(c4ccccc4Cl)c5C(=O)NC(=O)c5c3c2c1 6.8 CHEMBL1963785 CHEMBL386051 CSc1cccc(Nc2ncc3C=C(C(=O)N(C)c3n2)c4c(Cl)cccc4Cl)c1 9.7 CHEMBL1227835 CHEMBL391724 CSc1nc(NCc2ccccc2F)c3cnn(CC(Cl)c4ccccc4)c3n1 7.1 CHEMBL1056610 CHEMBL392301 CCSc1nc(NCCc2ccccc2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.89 CHEMBL1056610 CHEMBL394619 Cc1cccc(NC(=O)Nc2ccc(cc2)c3csc4ccnc(N)c34)c1 6.4 CHEMBL1963785 CHEMBL396523 OC(=O)c1ccccc1Nc2ccnc(Nc3ccc4[nH]ncc4c3)n2 6.3 CHEMBL1963785 CHEMBL398279 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN4CCCC4)nc12)c5cc(O)ccc5Br 9 CHEMBL923928 CHEMBL398845 CCN(CC)CCN1CCC(CC1)S(=O)(=O)c2ccc(Nc3nnc4cc(cc(C)c4n3)c5cc(O)ccc5Cl)cc2 8.46 CHEMBL923928 CHEMBL399246 CN1CCN(CC1)C(=O)c2ccc(Nc3nnc4cc(cc(C)c4n3)c5cc(O)ccc5Cl)cc2 9.3 CHEMBL923928 CHEMBL399268 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)CCCN4CCCC4)nc12)c5cc(O)ccc5Cl 8.77 CHEMBL923928 CHEMBL399438 N#Cc1cnc2cc(ccc2c1N[C@@H]3C[C@H]3c4ccccc4)c5ccc(CN6CCOCC6)cc5 6.52 CHEMBL923923 CHEMBL399627 CSc1nc(Nc2cccc(Br)c2)c3cnn(CC(Cl)c4ccc(F)cc4)c3n1 6.82 CHEMBL1056610 CHEMBL400211 CSc1nc(Nc2cccc(Cl)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.22 CHEMBL1056610 CHEMBL400303 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN4CCCC4)nc12)c5c(Cl)ccc(O)c5Cl 7.57 CHEMBL923928 CHEMBL400402 Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)c5cc(O)ccc5Cl 8.89 CHEMBL923928 CHEMBL400403 Cc1cc(cc2nnc(Nc3ccc(cc3)C(=O)NCCN4CCCC4)nc12)c5cc(O)ccc5Cl 8.59 CHEMBL923928 CHEMBL401238 CSc1nc(Nc2ccccc2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.4 CHEMBL962773 CHEMBL401251 COCCOc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c4ccccc4)c2cc1OC 6.41 CHEMBL923923 CHEMBL401447 CCCSc1nc(Nc2cccc(Cl)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.82 CHEMBL1056610 CHEMBL402288 Fc1cccc(CSc2nnc(NC(=O)c3ccccc3Cl)s2)c1 6.57 CHEMBL932076 CHEMBL402568 [O-][N+](=O)c1ccc(CSc2nnc(NC(=O)c3ccc(Cl)cc3)s2)cc1 7.04 CHEMBL932076 CHEMBL402891 COc1ccc(CSc2nnc(NC(=O)c3ccc(F)cc3)s2)cc1 6.71 CHEMBL932076 CHEMBL403402 Nc1n[nH]c2nccc(c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12 7.1 CHEMBL1963785 CHEMBL403731 Clc1ccc(cc1)C(=O)Nc2nnc(SCc3ccc(Br)cc3)s2 7.33 CHEMBL932076 CHEMBL404366 Cn1nc(N)c2c(cncc12)c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3 6.5 CHEMBL1963785 CHEMBL404666 CC(C)(C)N1CN(C(=C2C=NN=C12)N)c3ccc(Cl)cc3 6.28 CHEMBL962773 CHEMBL406658 Fc1ccc(CNc2ncnc3c2cnn3CC(Cl)c4ccc(Cl)cc4)cc1 7.1 CHEMBL948149 CHEMBL406845 CC(C)(C)n1nc(c2ccc(Cl)cc2)c3c(N)ncnc13 7.1 CHEMBL1963785 CHEMBL40798 CCCCNc1nc(SC)nc2c1cnn2CC(Cl)c3ccccc3 5.92 CHEMBL962773 CHEMBL408291 Clc1cccc(CSc2nnc(NC(=O)c3ccccc3Cl)s2)c1 6.12 CHEMBL932076 CHEMBL408966 ClC(Cn1ncc2c(NCc3cccc(Cl)c3)ncnc12)c4ccc(Cl)cc4 7.1 CHEMBL948149 CHEMBL409082 Fc1ccc(cc1)C(=O)Nc2nnc(SCc3ccccc3)s2 7.16 CHEMBL932076 CHEMBL409349 Cc1cc(C)cc(NC(=O)Nc2ccc(cc2)c3cccc4onc(N)c34)c1 6.3 CHEMBL1963785 CHEMBL410931 Fc1ccc(cc1)C(Cl)Cn2ncc3c(NCc4ccccc4)ncnc23 6.36 CHEMBL948149 CHEMBL411043 ClC(Cn1ncc2c(NCc3ccccc3)ncnc12)c4ccccc4 6.4 CHEMBL948149 CHEMBL412298 Fc1cccc(CNc2ncnc3c2cnn3CC(Cl)c4ccccc4)c1 7.4 CHEMBL948149 CHEMBL415264 CSc1nc(NCCc2ccc(C)cc2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.43 CHEMBL1056610 CHEMBL41910 CCCCNc1nc(SCC)nc2c1cnn2CC(Cl)c3ccccc3 6.5 CHEMBL2411063 CHEMBL428029 CCSc1nc(Nc2cccc(Cl)c2)c3cnn(CC(Cl)c4ccccc4)c3n1 7.4 CHEMBL1056610 CHEMBL429600 Fc1ccc(cc1)C(Cl)Cn2ncc3c(NCc4cccc(Cl)c4)ncnc23 6.92 CHEMBL948149 CHEMBL436137 Cc1cccc(C)c1c2cc(C)c3nc(Nc4ccc(OCCN5CCCC5)cc4)nnc3c2 7.96 CHEMBL923928 CHEMBL438610 O=C(Nc1ccccc1)Nc2nnc(Cc3ccccc3)s2 4.24 CHEMBL859157 CHEMBL440963 Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN4CCCC4)nc12)c5c(F)ccc(O)c5F 8.47 CHEMBL923928 CHEMBL443929 CCCNc1nc(SC)nc2c1cnn2CC(Cl)c3ccc(F)cc3 6.24 CHEMBL962773 CHEMBL453358 CSc1nc(NCCc2ccccc2F)c3cnn(CC(Cl)c4ccccc4)c3n1 6.4 CHEMBL962773 CHEMBL454119 CCCCNc1nc(SC)nc2c1cnn2CC(Cl)c3ccc(F)cc3 6.96 CHEMBL962773 CHEMBL454120 CCSc1nc(N(CC)CC)c2cnn(CC(Cl)c3ccccc3)c2n1 6.48 CHEMBL962773 CHEMBL454144 CCCNc1nc(SC)nc2c1cnn2CC(Br)c3ccccc3 6.06 CHEMBL962773 CHEMBL454922 CCCCNc1nc(SCCC)nc2c1cnn2CC(Cl)c3ccccc3 6.28 CHEMBL962773 CHEMBL454923 CCCSc1nc(NCc2ccccc2)c3cnn(CC(Cl)c4ccccc4)c3n1 7 CHEMBL962773 CHEMBL455163 CCOCCNc1nc(SC)nc2c1cnn2CC(Br)c3ccccc3 6.26 CHEMBL962773 CHEMBL455164 CSc1nc(N2CCCCC2)c3cnn(CC(Br)c4ccccc4)c3n1 6.06 CHEMBL962773 CHEMBL473102 CSc1nc(NCCc2ccccc2)c3cnn(CC(Cl)c4ccc(F)cc4)c3n1 6.7 CHEMBL962773 CHEMBL473103 CSc1nc(N2CCOCC2)c3cnn(CC(Br)c4ccccc4)c3n1 6.01 CHEMBL962773 CHEMBL473516 CSc1nc(NCc2ccccc2)c3cnn(CC(Br)c4ccccc4)c3n1 6.72 CHEMBL962773 CHEMBL473517 CSc1nc(NCCc2ccccc2)c3cnn(CC(Br)c4ccccc4)c3n1 6.57 CHEMBL962773 CHEMBL473726 CN(C)c1nc(NCc2ccccc2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.8 CHEMBL962773 CHEMBL473727 CCCNc1nc(nc2c1cnn2CC(Cl)c3ccccc3)N(C)C 6.5 CHEMBL962773 CHEMBL473923 CN(C)c1nc(N2CCOCC2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.55 CHEMBL962773 CHEMBL475336 CCCNc1nc(SC)nc2c1cnn2CC(Cl)c3ccc(Cl)cc3 6.4 CHEMBL962773 CHEMBL475337 CCCCNc1nc(SC)nc2c1cnn2CC(Cl)c3ccc(Cl)cc3 6.41 CHEMBL962773 CHEMBL475739 CSc1nc(N2CCOCC2)c3cnn(CC(Cl)c4ccc(F)cc4)c3n1 6.01 CHEMBL962773 CHEMBL475740 CSc1nc(NCc2ccc(F)cc2)c3cnn(CC(Cl)c4ccc(F)cc4)c3n1 6.66 CHEMBL962773 CHEMBL476303 Clc1ccc(Cc2cnc(NC(=O)c3cccs3)s2)c(Cl)c1 5.46 CHEMBL983798 CHEMBL476304 COc1ccc(Cc2cnc(NC(=O)c3cccs3)s2)cc1 7.8 CHEMBL983798 CHEMBL476513 Cc1ccc(Cc2cnc(NC(=O)c3cccs3)s2)cc1 6.6 CHEMBL983798 CHEMBL476514 Fc1ccc(cc1)c2cnc(NC(=O)c3cccs3)s2 5.78 CHEMBL983798 CHEMBL476515 Clc1ccc(cc1)c2cnc(NC(=O)c3cccs3)s2 6.1 CHEMBL983798 CHEMBL477139 COc1ccc2c(Cc3sc(NC(=O)c4cccs4)nc23)c1 7.17 CHEMBL983798 CHEMBL477342 O=C(Nc1nnc(COc2ccccc2)s1)c3cccs3 6.56 CHEMBL983798 CHEMBL477343 FC(F)(F)c1cccc(Cc2cnc(NC(=O)c3cccs3)s2)c1 6.87 CHEMBL983798 CHEMBL477344 Fc1ccccc1Cc2cnc(NC(=O)c3cccs3)s2 6.77 CHEMBL983798 CHEMBL477554 Clc1ccc(Cc2cnc(NC(=O)c3cccs3)s2)cc1 6.21 CHEMBL983798 CHEMBL477555 FC(F)(F)c1ccc(Cl)c(Cc2cnc(NC(=O)c3cccs3)s2)c1 6.07 CHEMBL983798 CHEMBL477772 CN(c1ccc2c(C)n(C)nc2c1)c3ccnc(Nc4ccc(C)c(c4)S(=O)(=O)N)n3 6.5 CHEMBL1963785 CHEMBL478181 Fc1ccc(Cc2cnc(NC(=O)c3cccs3)s2)cc1 6.89 CHEMBL983798 CHEMBL478825 O=C(Nc1nnc(Cc2ccccc2)s1)c3cccs3 6.44 CHEMBL983798 CHEMBL482967 Cc1nc(N)sc1c2ccnc(Nc3ccc(cc3)N4CCOCC4)n2 6.2 CHEMBL1963785 CHEMBL483158 COc1cccc(F)c1C2=NCc3cnc(Nc4ccc(C(=O)O)c(OC)c4)nc3c5ccc(Cl)cc25 6.3 CHEMBL1963785 CHEMBL49120 CCN(CC)CCOc1ccc(Nc2ncc3C=C(C(=O)N(C)c3n2)c4c(Cl)cccc4Cl)cc1 9.3 CHEMBL1963785 CHEMBL491473 COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN5CCCC5 7 CHEMBL1963785 CHEMBL504598 O=C(Nc1ncc(Cc2ccccc2)s1)c3cccs3 7.05 CHEMBL983798 CHEMBL507594 CSc1nc(N2CCCC2)c3cnn(CC(Br)c4ccccc4)c3n1 5.85 CHEMBL962773 CHEMBL508027 CCCCNc1nc(SC)nc2c1cnn2CC(Br)c3ccccc3 6.5 CHEMBL962773 CHEMBL508928 Cc1cccc(NC(=O)Nc2ccc(cc2)c3cnc4c(cnn4c3N)c5cnn(C)c5)c1 7.6 CHEMBL1963785 CHEMBL50894 [O-][N+](=O)c1ccc2[nH]c3c(CC(=O)Nc4ccccc34)c2c1 5.8 CHEMBL1963785 CHEMBL508986 CCCSc1nc(N(CC)CC)c2cnn(CC(Cl)c3ccccc3)c2n1 6.55 CHEMBL962773 CHEMBL509032 COc1cc(ccc1Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)N4CCC(CC4)N5CCN(C)CC5 6.6 CHEMBL1963785 CHEMBL510861 CCCNc1nc(SCCC)nc2c1cnn2CC(Cl)c3ccccc3 6.6 CHEMBL962773 CHEMBL514140 CSc1nc(NCc2ccccc2F)c3cnn(CC(Cl)c4ccc(F)cc4)c3n1 6.47 CHEMBL962773 CHEMBL515135 CCN(CC)c1nc(SC)nc2c1cnn2CC(Cl)c3ccc(Cl)cc3 6.52 CHEMBL962773 CHEMBL515885 CSc1nc(N2CCOCC2)c3cnn(CC(Cl)c4ccc(Cl)cc4)c3n1 6.3 CHEMBL962773 CHEMBL516070 CSc1nc(Nc2cccc(F)c2)c3cnn(CC(Cl)c4ccc(F)cc4)c3n1 6.66 CHEMBL962773 CHEMBL517047 Cc1cccc(Cc2cnc(NC(=O)c3cccs3)s2)c1 7.23 CHEMBL983798 CHEMBL517204 Clc1ccccc1Cc2cnc(NC(=O)c3cccs3)s2 6.61 CHEMBL983798 CHEMBL517822 Clc1ccc(Cl)c(Cc2cnc(NC(=O)c3cccs3)s2)c1 7.3 CHEMBL983798 CHEMBL518430 Clc1cccc(Cc2cnc(NC(=O)c3cccs3)s2)c1 7.01 CHEMBL983798 CHEMBL522892 CN1CCN(CC1)c2ccc3nc([nH]c3c2)C4=C(N)c5c(F)cccc5NC4=O 7 CHEMBL1963785 CHEMBL546797 ON=C(c1nc2ccccc2[nH]1)c3nc4ccccc4[nH]3 5.9 CHEMBL1963785 CHEMBL550418 COc1cc(ccc1O)c2ccc3C(=O)Nc4cccc(O)c4Nc3c2 6.1 CHEMBL1963785 CHEMBL551542 COc1ccc(CNc2nc(SC)nc3c2cnn3CC(Cl)c4ccccc4)cc1 6.52 CHEMBL1056610 CHEMBL553 COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC 6.4 CHEMBL1963785 CHEMBL564746 CSc1nc(NCCc2ccc(Cl)cc2)c3cnn(CC(Cl)c4ccccc4)c3n1 6.46 CHEMBL1056610 CHEMBL572878 CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(Sc4ccc(NC(=O)C5CC5)cc4)n2 7.8 CHEMBL1963785 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 7.6 CHEMBL1963785 CHEMBL577269 CN1C(=O)C(=Cc2cnc(Nc3cccc(N)c3)nc12)c4c(Cl)cccc4Cl 10.7 CHEMBL1227835 CHEMBL685 COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c3ccccc3 5.34 CHEMBL2033711 CHEMBL83847 CCN(CC)c1nc(SC)nc2c1cnn2CC(Cl)c3ccccc3 6.4 CHEMBL962773 CHEMBL941 CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1 7.3 CHEMBL1963785