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\ p None B a = c @ = Z ?N*8 X" 1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial General `
Table_1 b k ^ With fractures (n = 18)" Without fractures (n = 265) P Gender (M:F) 5:13 86:179 0.9 Age (yr) 61.5 15.2 55.4 15.9 0.1 Disease duration (yr) 16.7 14.1
10.9 9.5~ 0.048*
MG subtype E a r l y - o n s e t 9 (50%) 121(46%) 0.7 L a t e - o n s e t 5 (28%) 72 (27%) 1 T h y m o m a - a s s o c i a t e d 4 (22%) MG status M i n i m a l m a n i f e s t a t i o n o r b e t t e r 118 (45%) 0.2 Total quantitative MG score 22.1 13.3 6.8 4.8 <0.0001* Prednisolone treatment M a x i m u m d o s e ( m g / d ) 39.7 21.1 30.6 19.0 0.08 C u r r e n t d o s e ( m g / d ) 8.7 7.4 6.0 6.4 1 - y e a r t o t a l d o s e ( m g ) 2977 2456 2044 1862 D u r a t i o n o f t r e a t m e n t ( y r ) 12.1 10.4 6.4 6.2} 0.02* Risk factors B o d y m a s s i n d e x
23.8 4.7
22.8 3.7 0.6 P a r e n t a l h i p f r a c t u r e 0 7 (3%) C u r r e n t s m o k i n g 3 (16%) 33 (12%) 0.8 E x c e s s o f a l c o h o l i n t a k e 1 (6%) 11 (4%) R h e u m a t o i d a r t h r i t i s 3 (1%) 0.5 Bone mineral density F e m o r a l n e c k T s c o r e
"2 . 0 1 . 3
"1 . 1 1 . 1 ~ 0.003* L u m b a r s p i n e T s c o r e "1 . 9 1 . 2 ( n = 1 4 ) "0 . 9 1 . 6 ( n = 1 8 0 ) 0.3 Bone markers S e r u m N T x ( m m o l B E C / L )
15.5 4.2
13.9 6.3} 0.04* S e r u m B A P ( g / L )
12.8 4.8
11.8 6.0 Treatment
V i t a m i n D 71 (27%) C a l c i u m 24 (9%) B i s p h o s p h o n a t e s 11(61%) 135 (51%) 0.4
d MbP?_ % * + &P &F