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\ p None B a = c @ = Z ?N*8 X" 1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial General ` ] Table_1 f ; Pathologies Organ involved- Associated oxidizedlipid/anti-lipid Ab Origin of oxidizedlipid Method of detection Reference- Alzheimer disease, vascular demented patients CNS 24S-hydroxycholesterol Plasma ID-MS
[14] Alzheimer disease Plasma, cerebrospinalfluid
[49] Multiple sclerosis
[15] 27-hydroxycholesterol Brain tissue GC-MS
[50] Hereditary spastic paresis, 27-hydroxycholesterol, 25-hydroxycholesterol
[51] Atherosclerosis CardiovascularD 2 7 - h y d r o x y c h o l e s t e r o l , 2 5 - h y d r o x y c h o l e s t e r o l , 7 - h y d r o x y c h o l e s t e r o l HP-LC
[52] Parkinson disease F ( 2 ) - i s o p r o s t a n e s , h y d r o x y e i c o s a t e t r a e n o i c a c i d p r o d u c t s , 7 - h y d r o x y c h o l e s t e r o l , 2 7 - h y d r o x y c h o l e s t e r o l , 7 - k e t o c h o l e s t e r o l , n e u r o p r o s t a n e s ( F ( 4 ) N P s )
[17] 7-ketocholesterol
Serum, CSF
[53]F Oxidized phosphatidylcholine (OxPC)Anti-OxPC (T15 Idiotype) antibodies Brain extracts, CSF Western blotting,
[16] SLE Different organ systems Anti-cardiolipin Ab Serum ELISA
[54] Immunoglobulin A deficiency
[55] Antiphospholipid syndrome
[56] Systemic Lupus Erythematosus 15-F2t-IsoP
[57]