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\ p None B a = c @ = Z ?N*8 X" 1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial General ` Table 3 4 4 Gene* Gene Function AHNAK2. Unknown; a component of the costameric network CDH3+ A calcium-dependent cell adhesion molecule. CEACAM5 Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling; binds with another CEACAM to function. CEACAM6q A c e l l a d h e s i o n m o l e c u l e ; m e d i a t e s c e l l a d h e s i o n b y b i n d i n g w i t h a n o t h e r C E A C A M ( "1 , "5 , a n d "6 a r e m o s t c o m m o n ) . CLDN18 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity COL11A1^ This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. COL1A1^ Type 1 collagen is a fibril forming collagen found in most connective tissue; alpha chain one. COL1A2^ Type 1 collagen is a fibril forming collagen found in most connective tissue; alpha chain two. CTHRC1r May play a role in the cellular response to arterial injury through involvement in vascular remodeling. (secreted) CTSEK A gastric aspartyl protease that functions as a disulfide-linked homodimer. EPPK1A Unknown. May play a role in supporting the intermediate filaments FN1 Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. (secreted) GPRC5Ag Unknown. May be involved with the interaction between retanoic acid and the G protein sigaling pathway. IGHG3+ Unknown; Immunoglobulin heavy chain gamma 3 KRT19 Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. MMP11/ Weakly degrades structural proteins of the ECM. MUC4z Mucins are glycoprotein that play a role in the protection of epithelial cells. Implicated in renewal and differentiation. OLFM4~ An antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. POSTNH Induces cell attachment and spreading and plays a role in cell adhesion. S100P S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. SERPINB5j Unknown. Exhibits no serine protease inhibitory activity functions as a tumor suppressor of mammary tumors SLC6A14W A member of the solute carrier family; transports both neutral and cationic amino acids VCAN This protein is involved in cell adhesion, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance THBS2g A disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions COL3A1j Pro-alpha1 chain of type III collagen, a fibrillar collagen that is found in extensible connective tissue.
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