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\ p None B a = c @ = Z ?N*8 X" 1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial General `
Table_5 9
x Mutation of interacts via8 with mutations of genes with GO annotation P HOG1 Rule 41 invasive growth in response to glucose limitation 0.00027 TEC1 Rule 2 regulation of cellular process 0.00031 STE11 Rule 3% organelle organization and biogenesis 0.00053) positive regulation of biological process 0.00064 XBP1 Rule 5 reproduction 0.00070 ROX1 conjugation with cellular fusion 0.0010D positive regulation of transcription from RNA polymerase II promoter 0.0011 RAS2 SPO12 0.0012 MSN1 Rule 10 cell surface receptor linked signal transduction 0.0014 KSS1) positive regulation of catalytic activityS regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process HSL1% cell wall organization and biogenesis 0.0015 CDC42( positive regulation of metabolic process SRL1 0.0018 COD4 0.0019 response to pheromone 0.0021O pheromone-dependent signal transduction during conjugation with cellular fusion 0.0022 GLN3 protein targeting 0.0023 intracellular signaling cascade URE2 0.0025 YPS14 G-protein coupled receptor protein signaling pathway KTR2 DIG2 osmosensory signaling pathway 0.0027 PBS2 replicative cell aging 0.0031 cell communication response to chemical stimulus* regulation of transcription, DNA-dependent 0.0032 filamentous growth 0.0038 STE12 STE20 DSE1. cellular component organization and biogenesis 0.0039 0.0040 PRY2 0.0041 IPK1 0.0043" protein amino acid phosphorylation YPL114W developmental process 0.0045 0.0048 PDE2= response to pheromone during conjugation with cellular fusion TPK1 0.0049 YJL017W establishment of cell polarity MIH1 0.0051 growth 0.0052 RSR1 sporulation 0.0054 0.0055 M phase of mitotic cell cycle cellular metabolic process 0.0057 DBR1 mitotic cell cycle 0.0059\ negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.0060 0.0062 0.0065 0.0068 0.0071 CTS1 PHD1 protein localization 0.0073 RIM13 0.0076 CLN3 DIA3 BUD4 regulation of molecular function 0.0077 IME2 PAM1 cell morphogenesis biopolymer metabolic process 0.0081 GPR1 0.0082 BEM1 nitrogen utilization 0.0085 0.0087 0.0090 signal transduction pseudohyphal growth 0.0092( cellular macromolecule metabolic process 0.0093; regulation of transcription from RNA polymerase II promoter FLO8 0.0094 macromolecule metabolic process 0.0095
d MbP?_ % ^ * + &P &F